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University of Pennsylvania · Rehabilitation Medicine
Active 2008–2024
International Journal of Cancer · 2020 · 54 citations
levels found in a PDX from an outlier case with lethal outcome led to detection of similar profiles among recurrent HPV+ HNSCCs. Transcriptional data from the Cancer Genome Atlas was used to demonstrate that the lower E2F target gene expression predicted by reduced E7 levels has potential as a biomarker of disease recurrence risk. Our findings bridge a critical gap in preclinical models for HPV+ HNSCCs and simultaneously reveal novel potential applications of quantifying mutational burden and viral oncogene functions for biomarker development.
Zubair Baloch
Philadelphia University
Cindy McGrath
Tricia R. Bhatti
Lea F. Surrey
Children's Hospital of Philadelphia
PhdFit ranks faculty by your research interests, methods, and publications — grounded in their actual work, not templates.
Ken Kazahaya
University of Pennsylvania
Sogol Mostoufi‐Moab
Children's Hospital of Philadelphia
Amber Isaza
Children's Hospital of Philadelphia