About

Anil Ardeshna is an Associate Professor in the Department of Orthodontics at Rutgers School of Dental Medicine. His research focuses on cephalometrics, diagnostic and treatment measurements, and analysis related to orthodontics. His laboratory projects involve testing various materials using instruments such as the Instron machine, Differential Scanning Calorimeter, Dynamic Mechanical Analyzer, and Scanning Microscope. His investigations include studying skeletal and dentoalveolar growth and treatment changes in different types of malocclusion through cephalometric analysis, evaluating dimensional changes in extraction treatments with fixed appliances, and assessing palatal volume changes resulting from orthodontic treatments. Additionally, he explores microbial growth and the effects of disinfectants on orthodontic materials, the efficacy of fluoride-releasing sealants in resisting white spot lesions, and the microflora diversity in dental plaque biofilms on aligners and tooth surfaces. His work also encompasses the thermal behavior of nickel-titanium archwires, characterization of clear aligner materials, and the effects of stress and temperature on orthodontic elastomers.

Research topics

• Medicine
• Dentistry
• Biology
• Materials science
• Internal medicine
• Food science
• Chemistry
• Bioinformatics
• Composite material
• Intensive care medicine

Selected publications

• Maxillary Canine Substitution for a Central Incisor With Severe Root Resorption: A Case Report

  Case Reports in Dentistry · 2025-01-01

  articleOpen accessSenior authorCorresponding

  When maxillary canine emerges in an abnormal position, the so-called ectopic eruption, it can lead to issues that require a combination of surgical, orthodontic, pediatric, and restorative treatments. If the ectopic eruption causes damage to other teeth, they may need to be removed, and the remaining teeth repositioned and reshaped to achieve a functional and esthetic result. This process requires a team effort from pediatric dentists, orthodontists, radiologists, and surgeons and a knowledge of tooth anatomy, root positioning, and restorative techniques. This case report details the replacement of an impacted maxillary canine with a central incisor with a severely resorbed root.

  PublisherOA PDFDOI

• Systemic Factors Affecting Orthodontic Treatment Outcomes and Prognosis–Part 2

  Dental Clinics of North America · 2024-06-29 · 1 citations

  review1st authorCorresponding
  PublisherDOI

• Systemic Factors Affecting Orthodontic Treatment Outcomes and Prognosis – Part 1

  Dental Clinics of North America · 2024 · 1 citations

  • Medicine
  • Dentistry
  • Intensive care medicine
  PublisherDOI

• The enigma of sleep

  The Journal of the American Dental Association · 2024-07-14 · 6 citations

  review
  PublisherDOI

• Effectiveness of Different Sterilization Methods on Clinical Orthodontic Materials

  The Journal of Indian Orthodontic Society · 2022 · 8 citations

  1st authorCorresponding
  • Dentistry
  • Food science
  • Medicine

  Background Orthodontic appliances such as wires and brackets received from manufacturers come unsterilized and may be contaminated with various microorganisms before being used in the mouth. In this study, we evaluated and identified the bacterial contamination on orthodontic appliances along with the disinfecting efficacy of ultraviolet (UV) light and various sterilization methods. Methods Different orthodontic appliances were obtained from manufacturers divided into 5 sterilization methods and a control group (control, UV, dry heat and steam autoclave, ethyl alcohol, and 2% glutaraldehyde). Microbiological and DNA sequencing was performed on the appliances to identify the contaminated bacteria. Results Bacterial contamination identified on the orthodontic appliances were Staphylococcus aureus, Staphylococcus epidermidis, Lactobacilli, Klebsiella pneumoniae, Bacillus licheniformis, and Bacillus cereus. UV sterilization method effectively prevented the bacterial growth when compared to the control (unsterilized) orthodontic appliances. Conclusion We concluded that the orthodontic appliances received from the manufacturer showed bacterial contamination. All of the tested sterilization methods including UV light were effective in eliminating the bacterial contamination on the orthodontic appliances. Since UV light does not cause change in material properties and is cost effective with relative ease of use, its use in clinical practice for the disinfection of orthodontic appliances is suggested before placement in the mouth.

  PublisherDOI

• An In Vivo Study on the Development of Bacterial Microbiome on Clear Orthodontic Retainer

  Dentistry Journal · 2022 · 4 citations

  • Dentistry
  • Medicine
  • Biology

  OBJECTIVES: The objective of this study was to see how the bacterial composition changes on clear orthodontic retainer over a 14-day period. METHODS: Saliva and plaque samples collected from a clear retainer surface were obtained from five healthy volunteers receiving retainer treatment. Prior to clear retainer delivery, patients had not been wearing any other appliances. Patients were instructed to wear their clear retainer for the 14-day period, taking them off to eat and to clean them with a soft-bristle toothbrush. The bacterial composition was determined via Illumina MiSeq sequencing of the bacterial 16S rRNA. After bioinformatics processing using the QIIME pipeline, the intra- and intergroup biodiversity of the sample was analyzed. RESULTS: = 0.05) in the clear retainer when compared to saliva at 7 days. At the genus level, several microbiota were significantly increased in relative abundance in the clear retainer after the 14-day period. CONCLUSION: These findings reveal that the presence of a clear retainer in the mouth might lead to enamel changes or periodontal tissue destruction, especially after 14 days of use.

  PublisherOA PDFDOI

• Class II correction in orthodontic patients utilizing the Mandibular Anterior Repositioning Appliance (MARA)

  The Angle Orthodontist · 2019-01-02 · 22 citations

  articleOpen access1st authorCorresponding

  ABSTRACT Objectives: To evaluate skeletal and dentoalveolar changes produced by the Mandibular Anterior Repostioning Appliance (MARA) in the treatment of Class II malocclusion in adolescent patients. Materials and Methods: Lateral cephalograms of 24 patients, mean age 12.40 years, with a Class II malocclusion consecutively treated with MARA were compared with a historical control group. Changes were evaluated using the Pancherz superimposition and grid analysis pre- and posttreatment. Independent sample t-test, Mann-Whitney U-test, and Pearson correlation coefficient analysis were performed. Results: Significant differences were seen between the treatment and control groups during the 12 month period. Improvement in Class II relationship in the MARA group resulted from skeletal and dentoalveolar changes. There was a 7-mm molar correction and a 4.7-mm overjet reduction. There was also an increase in the mandibular base of 3.3 mm with the lower molar and incisor coming forward 2.6 mm and 2.2 mm, respectively. No significant headgear effect was shown on the maxilla. The maxillary incisor position remained unchanged, whereas the molar distalized 1.8 mm. The anterior lower facial height had an overall increase of 2.2 mm. Conclusions: The MARA was successful in achieving a Class I molar relationship and reducing the overjet in Class II malocclusions. This was the result of both skeletal and dentoalveolar changes.

  PublisherOA PDFDOI

• The Microflora Diversity and Profiles in Dental Plaque Biofilms on Brackets and Tooth Surfaces of Orthodontic Patients

  The Journal of Indian Orthodontic Society · 2019-06-27 · 13 citations

  articleOpen access

  Objective: Fixed orthodontic appliances may influence the oral environment through accumulation of plaque, decreased plaque pH, and increased gingival inflammation. These changes in the oral cavity can potentially lead to periodontal disease, demineralization, and other infectious diseases. Materials and Methods: To investigate the changes in biofilm throughout the initial 2 weeks, we placed a stainless steel bracket on the upper second premolar and collected plaque samples on the bracket and on the tooth surface at different time points (0, 24, 48 h and 1 and 2 weeks) and plated on tryptic soy agar blood agar plate, and kept at 37°C in an anaerobic chamber for 5 days to determine the CFUs of bacteria. At the end of 2 weeks, we removed the bracket and elastomeric module, and we isolated genomic DNA from the bacterial biofilm for identification of bacteria by 16S rRNA PCR analysis. We also analyzed the morphology of biofilm on the bracket by scanning electron microscope. Results: Our results show that the bacterial biofilm was significantly increased on the bracket in all the subjects, whereas on the tooth surface, the CFUs were not significantly increased. PCR assay showed that biofilm on orthodontic brackets from all subjects showed colonization by Streptococcus gordonii, Porphyromonas gingivalis and Streptococcus mutans were observed on some of the subjects after 48 h, whereas Aggregatibacter actinomycetemcomitans biofilm was observed in all the time points except 24 h. Conclusion: This study demonstrated that both periodontal and cariogenic bacterial biofilms were formed on the bracket as early as 24 h.

  PublisherOA PDFDOI

• The Effect of Rewards on Orthodontic Patient Compliance

  The Journal of Indian Orthodontic Society · 2018-07-01 · 2 citations

  articleOpen access1st authorCorresponding
  PublisherOA PDFDOI

• The Effect of Rewards on Orthodontic Patient Compliance

  The Journal of Indian Orthodontic Society · 2018-09-01 · 1 citations

  article1st authorCorresponding
  PublisherDOI

Frequent coauthors

• P. Emile Rossouw

  Eastman Chemical Company (United States)

  6 shared

• Manish Valiathan

  Case Western Reserve University

  3 shared

• Kabilan Velliyagounder

  Rutgers, The State University of New Jersey

  3 shared

• Shuying Jiang

  3 shared

• Sumit Gupta

  The University of Texas MD Anderson Cancer Center

  3 shared

• Tracey J Hendler

  2 shared

• Anjana Prakasam

  Rutgers, The State University of New Jersey

  1 shared

• T.K. Vaidyanathan

  1 shared

Labs

• OrthodonticsPI