Hayley Treloar Padovano
· Associate Director of Inclusive Excellence, Associate Professor of Psychiatry and Human Behavior, Associate Professor of Behavioral and Social SciencesVerifiedBrown University · Epidemiology
Active 2009–2026
About
Hayley Treloar Padovano is an Associate Professor of Psychiatry and Human Behavior at the Warren Alpert Medical School in the Division of BioMed and an Associate Professor of Behavioral and Social Sciences at the School of Public Health. She is a licensed psychologist and clinician scientist dedicated to teaching and research training. Her interdisciplinary research program focuses on studying multilevel determinants of health, wellness, and substance use, with particular interest in improving screening and brief interventions for chronic liver disease. Dr. Treloar Padovano has methodological expertise in laboratory alcohol administration, cue reactivity, ecological momentary assessment, and longitudinal data analysis. Since 2021, she has implemented all projects for which she is the primary researcher in both English and Spanish. She actively engages in service roles that oppose systems of disadvantage, fostering diverse perspectives and supporting free inquiry. Her leadership includes serving as co-chair of the Trainee Support branch of the Community and Belonging Council, participating in diversity and inclusion committees, and advising for the Office of Women in Medicine and Science. She is committed to ongoing learning about how privilege and resource access shape her viewpoint and contributes to the academic community through teaching and mentorship across various programs at Brown University.
Research topics
- Medicine
- Psychology
- Clinical psychology
- Psychiatry
- Social psychology
- Developmental psychology
- Environmental health
- Psychotherapist
- Family medicine
Selected publications
medRxiv · 2026-05-21
articleOpen accessSenior authorAbstract Background Alcohol use disorder (AUD) is marked by high relapse rates often driven by craving, yet less is known about whether in vivo , social, and place-based alcohol cues are differentially associated with craving across affective states. This study examined independent and affect-contingent associations of these cues with momentary craving in adults with AUD enrolled in an alcohol intervention study. Methods Thirty-three adults with AUD completed up to four daily ecological momentary assessments (EMA) for 28 days. EMA prompts assessed craving, in vivo alcohol exposure, being around usual drinking partners, being in usual drinking places, and high-arousal positive affect (PA) and negative affect (NA). Multilevel mixed-effects models adjusted for demographics, intervention phase (1 = post, 0 = pre), AUD severity, and temporal and contextual covariates. Results EMA compliance was high ( Median per-participant = 86.6%). Within-person elevations in in vivo alcohol exposure and being around usual drinking partners were independently associated with greater momentary craving, whereas being in usual drinking places was not. In vivo alcohol exposure was more strongly associated with craving during higher-than-usual PA ( β = 0.08, p = .032), whereas being in usual drinking places was more strongly associated with craving during higher-than-usual NA ( β = 0.06, p = .036), adjusting for intervention phase (which was associated with lower craving). Conclusions Findings support the need for personalized just-in-time adaptive interventions tailored to high-risk, momentary cue–affect contexts in AUD, beyond low-frequency clinician-delivered feedback that may reduce average craving but not fully address real-time risk. ClinicalTrials.gov registration: NCT05135767 .
PubMed · 2026-04-01
article1st authorCorrespondingOBJECTIVE: To evaluate the feasibility of a community- based, point-of-care (POC) screening and intervention model for Metabolic and Alcohol-associated Liver Disease (MetALD) in an underserved Rhode Island population. APPROACH: A partnership between the Brown University CADRE and Clínica Esperanza/Hope Clinic (CEHC) utilized electronic health record (EHR) screening followed by on-site FibroScan® imaging and a Motivational Interviewing (MI) lifestyle intervention. RESULTS: Preliminary pilot data identified liver stiffness (fibrosis) in 21% of participants and steatosis in 57%. All identified patients were previously unaware of their condition. CONCLUSIONS: Integrating POC diagnostics with culturally attuned behavioral interventions in a community- centric clinic can bypass traditional barriers to care and detect "silent" liver disease at treatable stages.
Situational correlates of adolescents’ alcohol outcome expectancies in daily life.
Psychology of Addictive Behaviors · 2025-05-15 · 2 citations
articleOpen accessSenior authorOBJECTIVE: Alcohol outcome expectancies (AOEs), formed in early childhood, are correlates of future alcohol consumption and related problems. Social-cognitive theories suggest that AOEs become activated in specific social and physical location contexts. Prior research, primarily among university students, has aimed to identify situational influences on specific AOEs, as indexed by reports of AOEs in hypothetical drinking scenarios. This study aims to deepen understanding of AOE activation in real-world settings by examining social and physical situational correlates of AOE activation among adolescents ages 15-17 in daily life. METHOD: = 102) reporting any drinking in the past month completed smartphone reports for 24 days. Adolescents indicated their social setting (e.g., solitary, peers, family), physical location (e.g., home, friend's place, elsewhere), and strength of AOEs (tension reduction, enhancement, sociability) just prior to drinking in daily life. RESULTS: Adolescents' AOE activation prior to drinking was associated with their immediate social context and physical location. Specifically, drinking with peers present was associated with higher ratings of enhancement and sociability AOEs. In contrast, drinking with family members present and drinking at home were associated with lower ratings of enhancement and sociability AOEs. CONCLUSIONS: Our findings provide new information about social-contextual correlates of specific AOE domains in naturalistic settings among adolescents. Identifying situational relations with AOE activation in daily life is important to build social-cognitive models of alcohol-consumption behavior, particularly during adolescence as drinking experiences broaden. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
Alcohol and Alcoholism · 2025-01-19 · 3 citations
articleOpen accessAIMS: We evaluated the safety, efficacy, and patient adherence to oral ANS-6637, a selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2), for treating alcohol use disorder (AUD). METHODS: A 3-arm, double-blind, randomized, proof-of-concept human laboratory study embedded in a 5-week multisite clinical trial tested 200 mg and 600 mg daily doses of ANS-6637 compared to placebo in treatment-seeking adults with AUD. After 1 week of medication, participants completed an alcohol cue reactivity session. Drinking and safety assessments were measured during treatment; other exploratory outcomes were measured 1 week after treatment ended. RESULTS: The study was terminated following enrollment of 43 of 81 planned participants due to clinically significant, reversible increases in liver enzymes in three women. Adverse events consistent with ALDH2 inhibition in the presence of alcohol (heart rate/palpitations, flushing, nausea) were dose dependent. Group differences in cue-elicited craving were not significant; effect sizes (Cohen's d) comparing the 200 mg and 600 mg doses to placebo were .71 and .06, respectively. Secondary endpoints did not differ significantly between groups; Cohen's d ranged from .31 to .57 for the 600 mg dose compared to placebo for continuous drinking outcomes. CONCLUSIONS: Findings of liver toxicity with ANS-6637 led to early termination and reduced power to test hypotheses. Effect size estimates are consistent with the hypothesis that selective ALDH2 inhibition may reduce craving and drinking, however these estimates may be unreliable due to the small sample size. Additional research with non-hepatotoxic selective and reversible ALDH2 inhibitors is needed to evaluate this approach to AUD pharmacotherapy.
2024-10-09
peer-reviewOpen access1st authorCorrespondingBackground Alcohol use is the third leading risk factor of death and disability in the UK and costs the NHS £3.5 billion per year. Despite the high prevalence and healthcare burden of Alcohol-related Liver Disease (ArLD), there has been minimal research addressing prevention, morbidity and mortality. Reasons for this include stigma and lack of interest from public, charitable and commercial funding bodies. The objectives of this project were to identify and develop interdisciplinary partnerships, to explore stigma in ArLD, to develop a representative Patient and Public Involvement and Engagement (PPIE) group, to build research capacity, and to develop interdisciplinary research proposals targeting key research priorities. Methods ArLD networks were identified by members of the Project Steering Group. Health Care Professionals (HCPs) from different backgrounds were invited to join the ARMS-Hub. PPIE representatives were invited through charities and support groups. Research areas were identified, discussed, prioritised and ranked. Research questions were refined during an in-person symposium. A mentorship programme was created to encourage and facilitate networking and knowledge exchange for early career researchers. Results We established the ARMS-Hub with 31 HCPs and 40 PPIE members. There were five stakeholder meetings, which included PPIE representation. Three virtual and three in-person PPIE meetings took place. Topics relevant to stigma in ARLD identified during the meetings were education and awareness, language, and access. Priorities identified were the disconnect between mental health and liver services, education around the wider harms of alcohol, and education of HCPs regarding stigma. We established a mentorship network that regularly meets to support development of new research ideas. Conclusions Stigma is central to lack of research engagement from professionals and PPIE. The main priority identified relates to the disconnect between mental health and liver services. This collaborative study has allowed development of a research agenda to address this priority.
2024-11-13
peer-reviewOpen access1st authorCorrespondingBackground Alcohol use is the third leading risk factor of death and disability in the UK and costs the NHS £3.5 billion per year. Despite the high prevalence and healthcare burden of Alcohol-related Liver Disease (ArLD), there has been minimal research addressing prevention, morbidity and mortality. Reasons for this include stigma and lack of interest from public, charitable and commercial funding bodies. The objectives of this project were to identify and develop interdisciplinary partnerships, to explore stigma in ArLD, to develop a representative Patient and Public Involvement and Engagement (PPIE) group, to build research capacity, and to develop interdisciplinary research proposals targeting key research priorities. Methods ArLD networks were identified by members of the Project Steering Group. Health Care Professionals (HCPs) from different backgrounds were invited to join the ARMS-Hub. PPIE representatives were invited through charities and support groups. Research areas were identified, discussed, prioritised and ranked. Research questions were refined during an in-person symposium. A mentorship programme was created to encourage and facilitate networking and knowledge exchange for early career researchers. Results We established the ARMS-Hub with 31 HCPs and 40 PPIE members. There were five stakeholder meetings, which included PPIE representation. Three virtual and three in-person PPIE meetings took place. Topics relevant to stigma in ARLD identified during the meetings were education and awareness, language, and access. Priorities identified were the disconnect between mental health and liver services, education around the wider harms of alcohol, and education of HCPs regarding stigma. We established a mentorship network that regularly meets to support development of new research ideas. Conclusions Stigma is central to lack of research engagement from professionals and PPIE. The main priority identified relates to the disconnect between mental health and liver services. This collaborative study has allowed development of a research agenda to address this priority.
Alcohol Clinical and Experimental Research · 2024-08-23 · 9 citations
articleBACKGROUND: Many individuals with excessive alcohol consumption desire moderation but do not seek formalized treatment. Commercially available, technology-assisted options are flexible and highly accessible, yet often not empirically validated. METHODS: Individuals desiring alcohol moderation (age 21+) self-selected to use Sunnyside®, a web application with tailored and adaptive text messaging. The evaluable dataset included 46,411 members who completed a baseline assessment, enrolled in the program, and tracked their drinking at least once. An adaptive and customizable weekly plan was generated from typical drinking patterns, goals, and weekly reported progress. Personalized daily messages included reminders for real-time drink tracking, plans, and available interactive messaging with peer coaches. Generalized mixed-effect growth models characterized change in drinks per week and daily drinking for 12 weeks after enrollment. Models allowed for nonlinear change and individual variability across members and weeks. RESULTS: A majority (64.3%) of members reported typically drinking 7 of 7 days per week at baseline. During tracking, drinks per week decreased most in the initial weeks and slowed thereafter, with an overall 33% reduction in weekly drink counts. More severe alcohol-use patterns and concern over drinking at baseline were associated with greater relative benefit. CONCLUSIONS: Drinking patterns appeared amenable to change during 12 weeks of daily drink tracking with Sunnyside®, a tailored web program to reduce drinking and improve overall wellness. Overall, the findings of this naturalistic study, one of the first of its kind, supplement data from randomized clinical trials and support the use of adaptive, technology-assisted tools for alcohol moderation.
Journal of Clinical Child & Adolescent Psychology · 2024-09-17 · 3 citations
articleOpen accessOBJECTIVE: This pre-registered analysis aimed to examine the moderating role of nicotine-use motives on the association between minority stress and nicotine use and craving among sexual minority youth. METHOD: = 1.10; 56.63% cisgender women; 73.5% non-Hispanic White). Participants were instructed to complete at least four assessments per day on wireless devices. Two types of multilevel models were estimated: models predicting day-level nicotine use and models predicting momentary nicotine use craving. RESULTS: Experiencing minority stressors was not associated with day-level nicotine use, but it was associated with greater momentary nicotine craving. Nicotine use-motives did not moderate the association between minority stress and nicotine use. In contrast, stress-reduction motives, assessed as a person-level trait, moderated the association between minority stress and nicotine craving, such that nicotine craving after experiencing a minority stressor was consistently higher relative to when minority stress had not been reported. Sensitivity analyses that examined associations between minority stress and nicotine use on a given day, regardless of temporal order, showed that minority stress was associated with higher odds of nicotine use on that day. CONCLUSIONS: : This study was preregistered at osf.io/w5sz9.
Alcohol Clinical and Experimental Research · 2024-03-04 · 6 citations
articleOpen accessBACKGROUND: Drinking commonly occurs in social settings and may bolster social reinforcement. Laboratory studies suggest that subjective effects and mood are mechanisms through which the social context influences alcohol consumption. Ecological momentary assessment (EMA) may be useful for extending these findings to the natural environment. This pre-registered secondary analysis of EMA data investigated the influence of the social environment on: (1) stimulating and sedating subjective effects of alcohol, (2) contentedness and negative affect, and (3) next-day evaluations of the drinking occasion. METHODS: = 28.09; 42% female) completed 7 days of EMA (in the morning, at random, and following drinking prompts), which included questions on their social context (drinking in the presence of known others or alone), contemporaneous stimulating and sedating effects, contentedness and negative affect, alcohol consumption, and next-day evaluations of a prior day's drinking event (how satisfying/pleasant was drinking). We used multi-level models in SAS 9.4 M7 software to examine relations among the variables. RESULTS: Contemporaneous subjective effects (stimulating or sedating), negative affect, and contentedness did not significantly depend on the social context. For next-day evaluations of pleasure/satisfaction from drinking, context effects were dependent on consumption totals. As the total number of standard drinks consumed increased, recollections of pleasure/satisfaction were higher when drinking had occurred with others, relative to alone. At lower consumption totals, next-day evaluations did not appear to depend on social context. CONCLUSIONS: When reported contemporaneously, subjective effects and affect do not appear dependent upon the presence of known others. However, heavier drinking events, relative to lighter drinking events, are appraised more favorably the following day when occurring within social contexts.
Alcohol-associated liver disease and behavioral and medical cofactors: unmet needs and opportunities
Frontiers in Public Health · 2024-04-04 · 1 citations
articleOpen accessChronic liver disease is a leading cause of death in the US and is often preventable. Rising burden, cost, and fatality due to liver disease are driven by intensified alcohol use in the US population and the contributions of comorbid conditions. This mini-review focuses on the topic of liver health in the context of chronic, behavioral cofactors of disease, using research-based examples from the Brown University Center for Addiction and Disease Risk Exacerbation (CADRE). Our aim is to illustrate the current challenges and opportunities in clinical research addressing liver health in the context of behavioral and medical comorbidity and to highlight next steps in this crucial area of public health research and clinical care.
Recent grants
Novel Approaches to Understanding How Alcohol Pathology Develops in Adolescents
NIH · $973k · 2017–2023
NIH · $2.6M · 2023–2028
NIH · $34.9M · 2019–2029
Frequent coauthors
- 136 shared
Robert Miranda
Brown University
- 37 shared
Samuel N. Meisel
- 27 shared
Peter M. Monti
- 25 shared
Thomas H. Chun
University of California, Los Angeles
- 23 shared
Alexander W. Sokolovsky
John Brown University
- 23 shared
Mollie A. Monnig
John Brown University
- 22 shared
Jennifer W. Tidey
Brown University
- 22 shared
Andrea M. Wycoff
University of Missouri
Education
Ph.D., Psychiatry and Human Behavior
Brown University
M.D.
Brown University
B.A.
Brown University
- Resume-aware match score
- Save to shortlist
- AI-drafted outreach
See your match with Hayley Treloar Padovano
PhdFit ranks faculty by your research interests, methods, and publications — grounded in their actual work, not templates.
- Free to start
- No credit card
- 30-second signup