
David B. Johnson
· Professor of Computer Science and of Electrical and Computer EngineeringVerifiedRice University · Computer Science
Active 1963–2025
About
David B. Johnson is a tenured full Professor in the Department of Computer Science and the Department of Electrical and Computer Engineering in the George R. Brown School of Engineering at Rice University. His home department is Computer Science, and he is also a member of the Ken Kennedy Institute for Information Technology at Rice. Before joining Rice's faculty in 2000, he was an Associate Professor in the School of Computer Science at Carnegie Mellon University for eight years. Prior to 1992, he was a Research Scientist and Lecturer in the Department of Computer Science at Rice University. He completed his Ph.D. in Computer Science at Rice in 1990, where his advisor was Willy Zwaenepoel, and also earned his M.S. and B.A. degrees from Rice, with a double major in Computer Science and Mathematical Sciences for his undergraduate degree. Professor Johnson's current research focuses on protocols for wireless and mobile networking. He leads the Monarch (MObile Networking ARCHitectures) research group at Rice University, which he founded in 1992 while at Carnegie Mellon University and has continued since moving to Rice. His work extensively covers Mobile IP and various types of multihop wireless networking, including mobile ad hoc networking, sensor networking, and mesh networking. He has been actively involved in the Internet Engineering Task Force (IETF), particularly in the Mobile IP and Mobile Ad Hoc Networks (MANET) working groups. Additionally, he served as Chair of ACM SIGMOBILE from 2005 through 2009 and currently serves on the ACM SIG Governing Board Executive Committee.
Research topics
- Sociology
- Political Science
- Computer Science
- Computer Security
- Public relations
- Economics
- Surgery
- Nuclear medicine
- Psychology
- Urology
- Biology
- Internal medicine
- Cancer research
- Gastroenterology
- Mathematics education
- Economic growth
- Oncology
- Business
- Medicine
Selected publications
Kidney International Reports · 2025-01-27
articleOpen accessDesigning a Cloud Chamber and Digital Twin Simulation for Studying Aerosol-Warm Cloud Interactions
2024-11-21
articleOpen accessAerosol micro-physics in smoke plumes: condensation, coagulation, and deposition
2024-11-21
articleOpen accessRegular and Young Investigator Award Abstracts · 2021 · 2 citations
- Medicine
- Internal medicine
- Gastroenterology
<h3>Background</h3> Tebentafusp, a bispecific fusion protein consisting of an affinity-enhanced T cell receptor fused to an anti-CD3 effector that can redirect T cells to target gp100+ cells, has shown an overall survival benefit for patients with untreated metastatic uveal melanoma (mUM) in a Ph3 trial (NCT03070392). Metastatic uveal melanoma (mUM) is a historically treatment-refractory tumor with 1-year (yr), 2-yr and 3-yr OS rates of 37%, 15% and 9%, respectively, and median OS of 7.8 months in 2L+ patients.<sup>1</sup> In the primary analysis of the phase 2 IMCgp100–102 study (NCT02570308) enrolling patients with previously treated mUM, the 1-year overall survival (OS) rate was 62% with median OS of 16.8 months.<sup>2</sup> We present updated OS and safety after 2-year follow-up. <h3>Methods</h3> 127 HLA-A*02:01+ 2L+ mUM patients were dosed weekly with tebentafusp following intra-patient dose escalation: 20mcg dose 1, 30mcg dose 2 and 68mcg dose 3+. Primary objective was ORR and secondary objectives included safety, OS and PFS. Here we present the updated OS and safety (data cut-off 31 Mar 2021). <h3>Results</h3> Median follow-up was 29.9 mos (range 1.8 – 59.9 mos). With extended follow-up, the 1-yr, 2-yr and 3-yr OS rates were 61%, 37% and 24%, respectively (figure 1). Median OS remained unchanged at 16.8 mos (95% CI, 12.8 – 22.5 mos).Mean and median duration of treatment were 9.5 mos and 5.6 mos (0 – 47.4 mos), respectively. As previously reported, most treatment-related AEs (TRAEs) occurred early on treatment. Beyond 6 months, no TRAE led to treatment discontinuation. No new safety signals, changes in the type or treatment-related deaths were reported. Beyond 12 months, there were a total of 7 Grade (G) 3 or 4 events in 3 (7%) patients, all were temporally related to tumor progression and majority included lab abnormalities. Episodes of rash, a common tebentafusp-related AE early on-treatment, were infrequent after 6 months, with no Grade 3 or 4 events. <h3>Conclusions</h3> This study provides the longest follow-up of OS and safety of a soluble TCR therapeutic to date. Tebentafusp continued to show promising survival for 2L+ mUM patients with estimated 2-yr OS rate of 37%. Tebentafusp’s safety profile was as expected and consistent with primary analysis showing that most adverse events occur early on treatment with incidence and severity decreasing with prolonged exposure. <h3>Trial Registration</h3> NCT02570308 <h3>References</h3> Rantala ES, Hernberg M, Kivela TT. Overall survival after treatment for metastatic uveal melanoma: a systematic review and meta-analysis. <i>Melanoma Res</i> 2019;<b>29</b>:561–568. Sacco JJ, Carvajal R, Butler MO, et al. A phase (ph) II, multi-center study of the safety and efficacy of tebentafusp (tebe) (IMCgp100) in patients (pts) with metastatic uveal melanoma (mUM). <i>Ann Oncol</i> 2020;<b>31</b>: S1442–S1143. <h3>Ethics Approval</h3> The institutional review board or independent ethics committee at each center approved the trial. The trial was conducted in accordance with the Declaration of Helsinki and the International Conference on Harmonization Good Clinical Practice guidelines.
PSID Main Interview User Manual: Release 2021
2021-01-01 · 1 citations
reportOpen accessThe Panel Study of Income Dynamics (PSID) is a household panel survey that began in 1968.This user manual serves as the primary source of documentation for the 2019 wave of the main interview.In addition, it provides critical information to users of the PSID such as the sample design, survey content, how to obtain the data, data quality, and much more.The manual includes important historical information about the survey, as well as information about the most recent data.For new users, this is the first document they should read before beginning to use the data.Through the years, thousands of pages of PSID documentation, guides to using the data, and other such resources have been distributed to users.The current document does not replace these prior documents.Instead, this document serves as a starting place for understanding the PSID, with a focus on describing changes in the key features over the years.Within this document we point users to documentation from prior years where historical information is described in greater detail.We expect the content of this manual to evolve and improve over time to meet the needs of the user community.Please contact us at psidhelp@umich.
Three Key Values of Generation Z: Equitably Serving the Next Generation of Students.
College and university · 2020 · 18 citations
1st authorCorresponding- Computer Science
- Sociology
- Political Science
PSID Main Interview User Manual: Release 2019
2019-01-01 · 1 citations
reportOpen accessRedesigning Traditional Programs to Meet the Needs of Generation Y
Journal of College Orientation Transition and Retention · 2019-01-01 · 3 citations
articleOpen access1st authorCorrespondingThe 14th American generation is defined as those born after 1981, numbering between 31 and 55 million people who are now arriving on college campuses. These students bring to campus distinctive characteristics, attitudes, and expectations for the collegiate experience. College and university orientation program administrators have an opportunity to adapt to this generation by examining their characteristics. The current discussion provides an outline of how orientation programs meet changing student needs. Specifically, they need to convey institutional concern for new students, demonstrated through creative, unique programming that expresses a caring attitude toward students.
ICPSR Data Holdings · 2019-01-01
datasetOpen accessKey macro indicators such as output, productivity, and inflation are based on a complex system across multiple statistical agencies using different samples and levels of aggregation. The Census Bureau collects nominal sales, the Bureau of Labor Statistics collects prices, and the Bureau of Economic Analysis constructs nominal and real GDP using these data and other sources. The price and quantity data are integrated at a high level of aggregation. This paper explores alternative methods for reengineering key national output and price indices using item-level data. Such reengineering offers the promise of greatly improved key economic indicators along many dimensions.
Automated English Proficiency Scoring of Unconstrained Speech Using Prosodic Features
2018-06-11 · 5 citations
articleSenior author
Frequent coauthors
- 17 shared
Willy Zwaenepoel
University of Sydney
- 15 shared
Yih‐Chun Hu
University of Illinois Urbana-Champaign
- 13 shared
John David N. Dionisio
Loyola Marymount University
- 13 shared
Ricky K. Taira
- 13 shared
Frank Paletta
Providence College
- 10 shared
Usha Sinha
San Diego State University
- 10 shared
Santashil PalChaudhuri
Rice University
- 9 shared
Michael Geologist
Mineral Resources
Labs
Awards & honors
- NSF CAREER Award (1998)
- ACM SIGMOBILE Distinguished Service Award (2001)
- Best Paper Award, the Twelfth ACM International Symposium on…
- Distinguished Faculty Associate, Lovett College, Rice Univer…
- Outstanding Faculty Associate, Lovett College, Rice Universi…
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