David Erickson
Cornell University · Nutrition
Active 1987–2024
About
Professor David Erickson is associated with the Bronfenbrenner Center for Translational Research at Cornell University. The center assists faculty in developing translational research projects, providing support such as proposal preparation, training, technical assistance, and fostering collaborative relationships. The center also offers workshops, summer institutes, and events focused on translational research methods and current research topics. While specific details about Professor Erickson's individual research focus or background are not provided in the page text, his affiliation with the center indicates a role in advancing translational research efforts within the university.
Research topics
- Computer Security
- Biology
- Risk analysis (engineering)
- Medicine
- Computer Science
- Software engineering
- Microbiology
- Intensive care medicine
- Pathology
- Bioinformatics
- Immunology
Selected publications
Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other Applications
Journal of Biomolecular Techniques JBT · 2021 · 55 citations
- Computer Science
- Computer Security
- Computer Science
As the second year of the COVID-19 pandemic begins, it remains clear that a massive increase in the ability to test for SARS-CoV-2 infections in a myriad of settings is critical to controlling the pandemic and to preparing for future outbreaks. The current gold standard for molecular diagnostics is the polymerase chain reaction (PCR), but the extraordinary and unmet demand for testing in a variety of environments means that both complementary and supplementary testing solutions are still needed. This review highlights the role that loop-mediated isothermal amplification (LAMP) has had in filling this global testing need, providing a faster and easier means of testing, and what it can do for future applications, pathogens, and the preparation for future outbreaks. This review describes the current state of the art for research of LAMP-based SARS-CoV-2 testing, as well as its implications for other pathogens and testing. The authors represent the global LAMP (gLAMP) Consortium, an international research collective, which has regularly met to share their experiences on LAMP deployment and best practices; sections are devoted to all aspects of LAMP testing, including preanalytic sample processing, target amplification, and amplicon detection, then the hardware and software required for deployment are discussed, and finally, a summary of the current regulatory landscape is provided. Included as well are a series of first-person accounts of LAMP method development and deployment. The final discussion section provides the reader with a distillation of the most validated testing methods and their paths to implementation. This review also aims to provide practical information and insight for a range of audiences: for a research audience, to help accelerate research through sharing of best practices; for an implementation audience, to help get testing up and running quickly; and for a public health, clinical, and policy audience, to help convey the breadth of the effect that LAMP methods have to offer.
Current state of the art in rapid diagnostics for antimicrobial resistance
Lab on a Chip · 2020 · 72 citations
- Intensive care medicine
- Risk analysis (engineering)
- Medicine
Antimicrobial resistance (AMR) is a fundamental global concern analogous to climate change threatening both public health and global development progress. Infections caused by antimicrobial-resistant pathogens pose serious threats to healthcare and human capital. If the increasing rate of AMR is left uncontrolled, it is estimated that it will lead to 10 million deaths annually by 2050. This global epidemic of AMR necessitates radical interdisciplinary solutions to better detect antimicrobial susceptibility and manage infections. Rapid diagnostics that can identify antimicrobial-resistant pathogens to assist clinicians and health workers in initiating appropriate treatment are critical for antimicrobial stewardship. In this review, we summarize different technologies applied for the development of rapid diagnostics for AMR and antimicrobial susceptibility testing (AST). We briefly describe the single-cell technologies that were developed to hasten the AST of infectious pathogens. Then, the different types of genotypic and phenotypic techniques and the commercially available rapid diagnostics for AMR are discussed in detail. We conclude by addressing the potential of current rapid diagnostic systems being developed as point-of-care (POC) diagnostic tools and the challenges to adapt them at the POC level. Overall, this review provides an insight into the current status of rapid and POC diagnostic systems for AMR.
Recent grants
A New Approach to Autonomous Point-of-care Tropical Disease Diagnostics Using Sol
NIH · $393k · 2013–2016
Early Stage Diagnosis of Kaposi's Sarcoma in Limited Resource Settings using KS-Detect
NIH · $3.2M · 2016–2023
NSF · $718k · 2014–2018
NSF · $288k · 2005–2008
Early Stage Diagnosis of Kaposi's Sarcoma in Limited Resource Settings using KS-Detect
NIH · $999k · 2016–2018
Frequent coauthors
- 52 shared
Saurabh Mehta
Cornell University
- 47 shared
Juan Boza
Cornell University
- 41 shared
Toby Maurer
Indiana University School of Medicine
- 41 shared
Aggrey Semeere
Makerere University
- 40 shared
Racheal Ayanga
Indiana University
- 39 shared
Stirling Bryan
Michael Smith Health Research BC
- 38 shared
Louisa Edwards
University of British Columbia
- 38 shared
Robert Lukande
Makerere University
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