
V. Ramesh Iyer
VerifiedUniversity of Pennsylvania · Rehabilitation Medicine
Active 2000–2026
About
V. Ramesh Iyer, M.D., M.B.B.S., is a Professor of Clinical Pediatrics (Cardiology) and an Attending Electrophysiologist in the Division of Cardiology at Children’s Hospital of Philadelphia. His educational background includes a B.Sc. from Hindu College, New Delhi, India, an MBBS from Maulana Azad Medical College, University of Delhi, an MD in Pediatrics from Safdarjang Hospital, and an MRCP in Pediatric and Neonatology residency from Royal College of Physicians, Edinburgh. He also holds a Master in Law from the University of Pennsylvania. His research expertise focuses on calcium signaling and electron microscopy in cardiac muscle ultrastructure in disease states such as hypertrophic cardiomyopathy and inherited ventricular tachycardias. He is involved in studying calcium release unit ultrastructure and modeling for sinus node functioning. His clinical expertise includes improving outcomes and reducing costs and fluoroscopy in patients undergoing complex ablations, as well as reducing time in ventricular fibrillation for ICD testing during initial implantation.
Research topics
- Medicine
- Internal medicine
- Cardiology
- Pediatrics
- Biophysics
Selected publications
PO-02-205 NOVEL TREATMENT OF BRUGADA SYNDROME PRESENTING IN INFANCY WITH MALIGNANT VT
Heart Rhythm · 2026-04-01
articleHeart Rhythm · 2025-04-01
articleHeart Rhythm · 2025-04-01
articleHeart Rhythm · 2025-04-01
articleOpen accessHeart Rhythm · 2025-04-01
articleHeart Rhythm · 2024-05-01
articleOpen accessHeart Rhythm · 2024-05-01
articleHeart Rhythm · 2024-01-21 · 8 citations
articleCirculation · 2024-11-12
articleBackground: Racial and ethnic disparities have been reported in catheter ablation in adults. There are limited data on the impact of race/ethnicity on the diagnosis and management of children with Wolff-Parkinson-White pattern (WPW). Hypothesis: Diagnosis of WPW by electrocardiogram (ECG) and risk stratification by exercise stress test (EST) and electrophysiology study (EPS) will differ by race/ethnicity in children. Methods: We performed a retrospective cohort study of patients 0-21 years old, excluding those with congenital heart disease, at a children’s hospital from 1991-2021. The primary exposure was race/ethnicity. Outcomes were 1) diagnosis of WPW on ECG, 2) undergoing EST, and 3) undergoing EPS. Likelihood and time to outcome were assessed with multivariable logistic regression adjusted for birth year and Cox regression, respectively. Results: The cohort consisted of 1,638,746 patients (White 53.0%, Black 21.0%, Hispanic 6.8%, Asian 4.2%, Multi-racial 2.0%, Other 11.0%, and Missing 1.7%). WPW was diagnosed in 898 patients (0.05%). After adjusting for birth year, Asian, Black, and Other race were associated with lower odds of WPW diagnosis compared to White patients (OR 0.57, 0.66, 0.70; p≤0.01). There was no association between race and age at first diagnosis (p=0.2). A total of 616 WPW patients (69%) underwent EST. Compared with White patients, Asian, Hispanic, and Other race were less likely to undergo EST (OR 0.39, 0.59, 0.62; p≤0.04), and those who did had their EST at later ages (HR 0.59, 0.65, 0.46; p≤0.04). A total of 739 WPW patients (82%) underwent EPS. Compared with White patients, Black, Hispanic, and Other race were less likely to undergo EPS (OR 0.44, 0.53, 0.59; p≤0.02), and those who did had their EPS at later ages (HR 0.60, 0.63, 0.66; p≤0.004). Conclusion: This analysis found that non-White racial and ethnic groups are less likely to be diagnosed with WPW. This may reflect differences in WPW prevalence by race/ethnicity, but differential access to ECG cannot be ruled out. Among WPW patients, however, Asian and Hispanic patients are approximately half as likely to undergo EST, while Black and Hispanic patients are approximately half as likely to undergo EPS, compared to White patients.
Pediatric Cardiology · 2023-08-06 · 6 citations
article
Frequent coauthors
- 51 shared
Victoria L. Vetter
Children's Hospital of Philadelphia
- 34 shared
Maully J. Shah
Children's Hospital of Philadelphia
- 31 shared
Christopher M. Janson
Children's Hospital of Philadelphia
- 20 shared
Noreen P. Dugan
- 18 shared
R. Lee Vogel
University of Pennsylvania
- 16 shared
Michael L. O’Byrne
Children's Hospital of Philadelphia
- 13 shared
Justine Shults
Children's Hospital of Philadelphia
- 12 shared
Clara Franzini‐Armstrong
University of Pennsylvania
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