Nancy B. Spinner
VerifiedUniversity of Pennsylvania · Rehabilitation Medicine
Active 1984–2024
Research topics
- Medicine
- Internal medicine
- Pediatrics
Selected publications
Outcomes of Childhood Cholestasis in Alagille Syndrome: Results of a Multicenter Observational Study
Hepatology Communications · 2020 · 80 citations
- Medicine
- Pediatrics
- Internal medicine
: This is the largest multicenter natural history study of cholestasis in ALGS, demonstrating a previously underappreciated burden of liver disease with early profound cholestasis, a second wave of portal hypertension later in childhood, and less than 25% of patients reaching young adulthood with their native liver. These findings will promote optimization of ALGS management and development of clinically relevant endpoints for future therapeutic trials.
Recent grants
NIH · $3.7M · 2008
NIH · $3.5M · 2016
NIH · $13.2M · 2003
NIH · $3.3M · 2018
Frequent coauthors
- 273 shared
Ian D. Krantz
Children's Hospital of Philadelphia
- 224 shared
Laura K. Conlin
University of Pennsylvania
- 187 shared
David A. Piccoli
- 151 shared
Kathleen M. Loomes
Children's Hospital of Philadelphia
- 119 shared
Elaine H. Zackai
Children's Hospital of Philadelphia
- 119 shared
Binita M. Kamath
SickKids Foundation
- 105 shared
Christopher M. Grochowski
Baylor College of Medicine
- 79 shared
Marcella Devoto
National Research Council
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