About

Albert M. Kligman was a faculty member in the Department of Dermatology at the University of Pennsylvania's Perelman School of Medicine. His contact information included an office located at 226 Crb, Philadelphia, PA 19104, with an email address akligman@mail.med.upenn.edu. The page indicates his association with the university's medical school and his role within the dermatology department, but does not provide specific details about his research focus, background, or key contributions.

Research topics

• Medicine
• Dermatology
• Chemistry
• Biology
• Gynecology

Selected publications

• An Improved Procedure for Assaying Irritants

  Current problems in dermatology · 2015-04-16 · 6 citations

  articleSenior author

  Influence of preferential diffusion on the dynamics of hydrogen and syngas nonpremixed impinging jet flames was studied using direct numerical simulation and flamelet generated manifolds based on detailed chemical kinetics. The results presented in this study were obtained from a uniform Cartesian grid with 768 × 768 × 768 points. Reynolds number used was Re = 2000, based on the reference quantities. Results reported here indicate that the preferential diffusion significantly affects the structures and the maximum temperature of the hydrogen flame, which deviates significantly from the results obtained without considering the preferential diffusion. The preferential diffusion results in a shift in the equivalence ratio in the reaction zone to leaner conditions. Moreover, the numerical results suggest that the preferential diffusion influences the flame–wall interaction and thus wall heat transfer, which is critical for the design of combustion equipment for clean combustion applications with high hydrogen contents in the fuel.

  PublisherDOI

• Cutaneous Toxicology: an Overview from the Underside

  Current problems in dermatology · 2015-04-16 · 12 citations

  review1st authorCorresponding
  PublisherDOI

• The Role of Adenosine Triphosphate in the Pathogenesis of Rosacea: An Explanation for the Mode of Action of Tetracyclines for the Treatment of Rosacea

  2014-01-01 · 1 citations

  book-chapter1st authorCorresponding
  PublisherDOI

• Rosacea: The State of the Art

  2014-01-01 · 1 citations

  book-chapter1st author
  PublisherDOI

• Erratum

  2014-01-01

  erratumSenior author
  PublisherDOI

• Wallace H. Clark

  2013-01-01

  book-chapter1st authorCorresponding
  PublisherDOI

• Corneobiology and Corneotherapy – a final chapter

  International Journal of Cosmetic Science · 2011-03-08 · 28 citations

  review1st authorCorresponding

  The text obtained for this review from Professor Albert Kligman was drawn posthumously from a variety of notes that he had been planning to use to write a review on corneobiology and corneotherapy. It was a review that he had dearly hoped to complete--his final 'magnum opus' with reflections on the subject.

  PublisherDOI

• Demodex folliculorum: Requirements for Understanding Its Role in Human Skin Disease

  Journal of Investigative Dermatology · 2010-12-14 · 84 citations

  articleOpen access1st author
  PublisherOA PDFDOI

• Preface

  Skin Pharmacology · 2009-04-06

  articleOpen access
  PublisherOA PDFDOI

• Stratum corneum Lipid Removal by Surfactants: Relation to in vivo Irritation

  Dermatologica · 2009-10-08 · 188 citations

  articleSenior author

  The relationship between the in vivo irritation potential of sodium lauryl sulfate (SLS) and linear alkyl benzene sulfonate (LAS) and the ability of these two surfactants to remove lipid from the stratum corneum (SC) in vitro were investigated. Either surfactant removes detectable levels of lipids only above its critical micelle concentration (CMC). At high concentrations the surfactants removed only very small amounts of cholesterol, free fatty acid, the esters of those materials, and possibly squalene. SLS and LAS have been shown, below the CMC, to bind to and irritate the SC. Thus, clinical irritation provoked by SLS or LAS is unlikely to be directly linked with extraction of SC lipid. The milder forms of irritation--dryness, tightness, roughness--may involve both surfactant binding to and denaturation of keratin as well as disruption of lipid. Our findings challenge earlier assumptions that surfactants' degreasing of the SC is involved in the induction of erythema.

  PublisherDOI

Frequent coauthors

• Gerd Plewig

  Ludwig-Maximilians-Universität München

  414 shared

• William D. James

  37 shared

• Tracy Stoudemayer

  34 shared

• William Montagna

  30 shared

• John S. Strauss

  Island Health

  29 shared

• Otto H. Mills

  Johnson University

  25 shared

• Kays H. Kaidbey

  20 shared

• Alessandra Pagnoni

  University of Lausanne

  19 shared

Education

• M.D.

  University of Pennsylvania