About

Eve De Rosa is associated with the Bronfenbrenner Center for Translational Research at Cornell University. The center assists faculty in developing translational research projects by providing proposal preparation assistance, training, technical support, and facilitating collaborative relationships. The center offers workshops, an intensive summer institute, and talks on current research to support researchers in their work. While specific details about her research focus or background are not provided in the available page text, her affiliation indicates involvement in translational research efforts aimed at applying research findings to practical and community settings.

Research topics

• Computer Science
• Artificial Intelligence
• Psychology
• Cognitive psychology
• Neuroscience
• Sociology
• Social psychology
• Internal medicine
• Mathematics
• Pedagogy
• Developmental psychology
• Audiology
• Communication

Selected publications

• Vagus nerve stimulation alters task‐evoked pupillary responses in older but not younger adults: A single‐blind active sham‐controlled crossover trial

  Alzheimer s & Dementia · 2026-02-01

  articleOpen access

  INTRODUCTION: The locus coeruleus (LC) undergoes age-related changes and is involved in Alzheimer's disease pathogenesis. Vagus nerve stimulation (VNS) may modulate LC activity and could be used therapeutically, but age-related differences in VNS responses remain unexplored. METHODS: We used a single-blind, sham-controlled, crossover design in 41 participants (21 younger, 20 older adults). Participants completed a visual oddball task with pupillometry during transcutaneous auricular VNS (verum: cymba concha; sham: earlobe) with ≈ 30 minutes of washout between conditions. RESULTS: Older adults showed smaller baseline pupil diameter but larger normalized task-evoked responses than younger adults a priori. VNS produced age-specific effects: older adults demonstrated increased tonic pupil size throughout stimulation and reduced oddball-evoked responses, with stronger effects with more current. Younger adults showed no consistent VNS effects. DISCUSSION: VNS affects LC-related physiological measures differently across age groups, with older adults showing more robust responses. These age-specific effects may reflect different baseline LC activity states.

  PublisherDOI

• Vagal nerve stimulation alters task-evoked pupillary responses in older adults but not younger adults in a single-blind sham-controlled crossover trial

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-10

  preprintOpen access

  Abstract Introduction The locus coeruleus (LC) undergoes age-related changes and is involved in Alzheimer’s disease pathogenesis. Vagal nerve stimulation (VNS) may modulate LC activity and could be used therapeutically, but age-related differences in VNS responses remain unexplored. Methods We used a single-blind, sham-controlled, crossover design in 41 participants (21 younger, 20 older adults). Participants completed a visual oddball task with pupillometry during transcutaneous auricular VNS (verum: cymba concha; sham: earlobe) with ∼30-minute washout between conditions. Results Older adults showed smaller baseline pupil diameter but larger normalized task-evoked responses than younger adults a priori. VNS produced age-specific effects: older adults demonstrated increased tonic pupil size throughout stimulation and reduced oddball-evoked responses, with stronger effects with more current. Younger adults showed no consistent VNS effects. Discussion VNS affects LC-related physiological measures differently across age groups, with older adults showing more robust responses. These age-specific effects may reflect different baseline LC activity states.

  PublisherOA PDFDOI

• Age-associated alterations of brain networks using dynamic ASL

  Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition · 2025-09-16

  article

  Motivation: Motion may affect age-related discrepancy in resting-state functional connectivity (rsFC) in BOLD imaging studies. Dynamic arterial spin labeling (DASL) offers an alternative, detecting large-scale network rsFC with fewer motion artifacts. However, the aging effects on DASL rsFC remain unexplored. Goal(s): We examined how brain networks evolve with age using DASL. Approach: We used a data-driven approach to measure rsFC within and between brain networks in 131 adults. Results: Older age correlated with reduced intra-network rsFC in the ventral stream (VSN), sensorimotor, left frontoparietal (LFPN), right frontoparietal, default mode (DMN), salience (SN), and frontal networks, and decreased inter-network rsFC between LFPN-SN, VSN-SN, and DMN-SN. Impact: The rsFC of DASL may offer additional knowledge about the aging brain in the healthy adults and increase our insight into the neural basis of neurodegenerative disease.

  PublisherDOI

• Science Democratization for Rigor, Relevance, and Resilience

  Developmental Psychobiology · 2025-08-21

  review

  Developmental psychobiology and neuroscience hold the promise to improve children's lives but also the peril to entrench marginalization when insights are misapplied or stripped of context. Diversification tilts us towards promise, but as political forces threaten inclusive research practices and public trust in science, developmental researchers face a critical moment. This paper argues that science democratization-grounded in care, inclusivity, and shared authority-can make our science more rigorous, relevant, and resilient. We begin by reviewing how gender, ethnoracial, and cognitive diversity among researchers and participants has expanded the field's reach and sharpened its questions. We then turn to democratization as a relational stance centering care and agency, with the enhancement of our science as a consequence. To ground this approach, we describe an illustrative gender-inclusion event led by the Community Neuroscience Initiative (CNI), which brought together scientists and community members for dialogue, shared learning, and collaboration. Finally, we offer readings, practical recommendations, and open questions for readers interested in applying these ideas to their own work. Written collaboratively with input from all stakeholders involved, this manuscript offers a timely vision for a more ethical, inclusive, and impactful developmental psychobiology and neuroscience.

  PublisherDOI

• Attention-dependent coupling with forebrain and brainstem neuromodulatory nuclei differs across the lifespan

  GeroScience · 2025-03-04 · 3 citations

  articleOpen access

  Attentional states reflect the changing behavioral relevance of stimuli in one's environment, having important consequences for learning and memory. Supporting well-established cortical contributions, attentional states are hypothesized to originate from subcortical neuromodulatory nuclei, such as the basal forebrain (BF) and locus coeruleus (LC), which are among the first to change with aging. Here, we characterized the interplay between BF and LC neuromodulatory nuclei and their relation to two common afferent cortical targets important for attention and memory, the posterior cingulate cortex and hippocampus, across the adult lifespan. Using an auditory target discrimination task during functional MRI, we examined the influence of attentional and behavioral salience on task-dependent functional connectivity in younger (19-45 years) and older adults (66-86 years). In younger adults, BF functional connectivity was largely driven by target processing, while LC connectivity was associated with distractor processing. These patterns are reversed in older adults. This age-dependent connectivity pattern generalized to the nucleus basalis of Meynert and medial septal subnuclei. Preliminary data from middle-aged adults indicates a transitional stage in BF and LC functional connectivity. Overall, these results reveal distinct roles of subcortical neuromodulatory systems in attentional salience related to behavioral relevance and their potential reversed roles with aging, consistent with managing increased salience of behaviorally irrelevant distraction in older adults. Such prominent differences in functional coupling across the lifespan from these subcortical neuromodulatory nuclei suggests they may be drivers of widespread cortical changes in neurocognitive aging, and middle age as an opportune time for intervention.

  PublisherOA PDFDOI

• A leadership ethics curriculum: Bringing mixed-methods interdisciplinary insights to the ethical complexities of health leadership

  Healthcare Management Forum · 2025-04-09 · 1 citations

  articleOpen access

  In response to the increasingly complex ethical issues facing health leaders, the Bioethics Department at The Hospital for Sick Children (a Canadian quaternary care paediatric research institution) was asked by senior leadership to develop a leadership ethics curriculum that would further develop the ability of its institution's leaders to deliberate and make morally defensible decisions in their roles. Insights from an interdisciplinary literature review suggest that the general objectives and structure of leadership ethics teaching remain constant, with specifics changing depending on the organization and intended participants. Implementing findings from an institutional needs assessment, our modular leadership ethics curriculum, which engages participants in asynchronous and synchronous learning, was designed to support (1) understanding of personal and organizational values, (2) recognizing the significance of attending to the ethical dimensions of decisions, (3) familiarity with leadership and organizational expectations, and (4) practicing application of ethical analysis, enhancing abilities and confidence to engage with ethical issues.

  PublisherDOI

• Blood oxygenation level-dependent responses in neuromodulatory nuclei and their associations with attention and memory across age groups

  Neurobiology of Aging · 2025-07-16 · 2 citations

  articleOpen accessSenior author
  PublisherOA PDFDOI

• Children Use Others’ Talk about Emotions to Make Social Choices

  SSRN Electronic Journal · 2025-01-01

  preprintOpen access
  PublisherDOI

• Age-related differences in locus coeruleus intensity across a demographically diverse sample

  Neurobiology of Aging · 2025-03-13 · 9 citations

  articleSenior author
  PublisherDOI

• Age and gender-related patterns of arterial transit time and cerebral blood flow in healthy adults

  NeuroImage · 2025-02-21 · 4 citations

  articleOpen access

  • We detect age-related arterial transit time (ATT) and ATT-corrected CBF patterns. • ATT increases with age in the frontal, temporoparietal, and occipital regions. • Without ATT correction, age-related CBF patterns generated artifact regions. • The findings emphasize ATT's role and its importance in CBF measurement for aging. Normal aging has been associated with increased arterial transit time (ATT) and reduced cerebral blood flow (CBF). However, age-related patterns of ATT and CBF and their relationship remain unclear. This is partly due to the lengthy scan times required for ATT measurements, which caused previous age-related CBF studies to not fully account for transit time. In this work, we aimed to elucidate age-related ATT and ATT-corrected CBF patterns. We examined 131 healthy subjects aged 19 to 82 years old using two pseudo-continuous arterial spin labeling (PCASL) MRI scans: one to measure fast low-resolution ATT maps with five post-labeling delays and the other to measure high-resolution perfusion-weighted maps with a single post-labeling delay. Both ATT and perfusion-weighed maps were applied with vessel suppression. We found that ATT increases with age in the frontal, temporoparietal, and occipital regions, with a more pronounced elongation in males compared to females in the middle temporal gyrus. ATT-corrected CBF decreases with age in several brain regions, including the anterior cingulate, insula, posterior cingulate, angular, precuneus, supramarginal, frontal, parietal, superior and middle temporal, occipital, and cerebellar regions, while remaining stable in the inferior temporal and subcortical regions. In contrast, without ATT correction, we detected artifactual decreases in the inferior temporal and precentral regions. These findings suggest that ATT provides valuable and independent insights into microvascular deficits and should be incorporated into CBF measurements for studies involving aging populations.

  PublisherDOI

Frequent coauthors

• Adam K. Anderson

  Cornell University

  31 shared

• York Broadway

  American Association For The Advancement of Science

  12 shared

• Khena M. Swallow

  Cornell University

  10 shared

• Leigh C.P. Botly

  University of Calgary

  9 shared

• Charles M. Ruffner

  Southern Illinois University Carbondale

  8 shared

• Ermanno Gherardi

  8 shared

• Ann Reyes Robbins

  St. Luke's-Roosevelt Hospital Center

  8 shared

• G Bedell

  Shanghai Shipbuilding Technology Research Institute

  8 shared

Awards & honors

• Current member of a National Institute of Aging - Neuroscien…