TE-STGCN: Topology enhanced spatio-temporal graph convolutional network for skeleton-based action recognition

Applied Soft Computing · 2026-02-14

Current orthodontic education status in the North American region on treating patients with obstructive sleep apnea

Frontiers in Oral Health · 2026-01-29

Objectives: In 2019, American Association of Orthodontists (AAO) published the white paper on obstructive sleep apnea (OSA) and orthodontics, eliciting the role of the orthodontic specialty in the management of OSA. This study aims to evaluate the current status of OSA management education in the North America region to identify areas for improvement to enhance orthodontic training and, ultimately, better patient health outcomes. Materials and methods: Multiple-choice survey links were distributed via Qualtrics to postgraduate orthodontic program directors and department chairs, requesting anonymous responses in July-September 2024. Results: The response rate was 36.5% (27 responses). 96% of respondents indicated that their program provided education on orthodontic management and treatment of OSA patients, while 74.1% reported having special protocols for managing these patients. However, teaching formats, faculty backgrounds, screening or treatment methods, and competency assessments had varying responses. Conclusion: In summary, it seems there is a lack of standardization in the post-graduate residency curriculum on OSA patient management.

ETMamba: An Effective Temporal Model for Video Action Recognition

Electronics · 2026-03-23

Video action recognition faces persistent challenges in balancing accuracy with computational efficiency. While state space models, such as Mamba, have emerged with linear complexity advantages, they exhibit inefficiency in capturing critical spatiotemporal dependencies within video data. To address this core limitation, this paper proposes ETMamba, an enhanced architecture built upon the Mamba baseline. The ETMamba achieve performance breakthroughs via three core innovation modules: (1) the Spatiotemporal Feature Preservation module retains complete original spatiotemporal correlations before data flattening, solving the problem of spatiotemporal feature loss; (2) the Efficient Bidirectional Sharing strategy accurately models bidirectional temporal dependencies, enhancing key temporal dynamic information; and (3) the Spatiotemporal Collaborative Modulation mechanism combines global temporal and local spatial information to achieve collaborative capture of long-short term dependencies and fine-grained features. We conduct experiments on multiple benchmark datasets, achieving recognition accuracies of 88.3%, 74.6%, 75.7%, and 98.1% on Kinetics-400, Something-Something V2, HMDB-51, and Breakfast datasets, respectively, while maintaining low to medium computational complexity.

Raman spectral fingerprinting links molecular and transcriptomic changes in mesenchymal stem cells during skeletal aging

Dental Research · 2026-01-01

Onsite assessment of airborne viral transmission risks in hospital: A computer vision-based approach considering multi-space occupant behavior

Building and Environment · 2025-03-11 · 1 citations

Fibromodulin selectively accelerates myofibroblast apoptosis in cutaneous wounds by enhancing interleukin 1β signaling

Nature Communications · 2025-04-12 · 6 citations

Activated myofibroblasts deposit extracellular matrix material to facilitate rapid wound closure that can heal scarlessly during fetal development. However, adult myofibroblasts exhibit a relatively long life and persistent function, resulting in scarring. Thus, understanding how fetal and adult tissue regeneration differs may serve to identify factors that promote more optimal wound healing in adults with little or less scarring. We previously found that matricellular proteoglycan fibromodulin is one such factor promoting more optimal repair, but the underlying molecular and cellular mechanisms for these effects have not been fully elucidated. Here, we find that fibromodulin induces myofibroblast apoptosis after wound closure to reduce scarring in small and large animal models. Mechanistically, fibromodulin accelerates and prolongs the formation of the interleukin 1β-interleukin 1 receptor type 1-interleukin 1 receptor accessory protein ternary complex to increase the apoptosis of myofibroblasts and keloid- and hypertrophic scar-derived cells. As the persistence of myofibroblasts during tissue regeneration is a key cause of fibrosis in most organs, fibromodulin represents a promising, broad-spectrum anti-fibrotic therapeutic.

Current Orthodontic Education Status on Treating Patients With ASD and/or ADHD in North America

Journal of Dental Education · 2025-10-24

OBJECTIVES: Autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD) are associated with specific dental and behavioral attributes, particularly in children, that necessitate special attention from healthcare providers. This study examines the training provided in postgraduate orthodontic programs in North America regarding the treatment of patients with ASD and/or ADHD. METHODS: A multiple-choice online survey was sent via Qualtrics requesting the anonymous participation of program directors/chairs of all 75 postgraduate orthodontic programs in North America. RESULTS: The survey response rate was 38.7% with 29 complete responses. Of the respondents, only 6.9% (two) had specific protocols to treat these patients in their postgraduate clinics. Most respondents did not teach about malocclusion differences (72.4%), other dental differences (55.2%), patient behavior management strategies (37.9%), or guardian communication strategies (65.5%) for patients with ASD and/or ADHD. Of the 20 programs that treat patients with ASD and/or ADHD in their postgraduate clinics, 60.0% of the respondents reported that they do not have specific requirements for faculty member(s) who provide clinical instructions on managing these patients. For the 13 programs that offer lectures on treating patients with ASD and/or ADHD, predominantly faculty member(s) with a craniofacial fellowship or faculty member(s) with more clinical experience in this area give the lectures. CONCLUSION: Few North American postgraduate orthodontic programs provide systematic education about treating patients with ASD and/or ADHD. There needs to be more consistency in the curriculum content. A standardized and systematic education curriculum is necessary to better prepare postgraduate trainees for treating children with ASD and/or ADHD.

LncRNA HOTAIR Interaction With WTAP Promotes m⁶A Methyltransferase Complex Assembly and Posterior Capsule Opacification Formation by Increasing THBS1

Investigative Ophthalmology & Visual Science · 2025-05-09 · 2 citations

Purpose: To explore the role of long non-coding RNAs (lncRNAs) and N6-methyladenosine (m6A) in posterior capsule opacification (PCO) and their underlying mechanisms. Methods: The localization of lncRNAs and proteins was analyzed using fluorescence in situ hybridization and immunofluorescence staining. RNA m6A quantification, RNA immunoprecipitation, co-immunoprecipitation, MeRIP-seq, MeRIP-qPCR, western blotting, wound healing, and Transwell assays were applied to elucidate the underlying mechanisms. Results: The levels of lncRNA HOX transcript antisense intergenic RNA (HOTAIR) and m6A methylation increased significantly during epithelial-mesenchymal transition (EMT) in lens epithelial cells (LECs). HOTAIR promoted EMT and m6A methyltransferase activity but had no effect on methyltransferase activity and was not modified by m6A. Nevertheless, HOTAIR interacted with WT1-associated protein (WTAP), a key m6A writer protein, facilitating WTAP-mediated recruitment of METTL3-METTL14 heterodimers and enhancing m6A modification. The HOTAIR/WTAP complex elevated m6A levels, thrombospondin 1 (THBS1) expression, and EMT in LECs. Conclusions: LncRNA HOTAIR enhances the assembly of the WTAP/METTL3/METTL14 complex and promotes EMT in LECs by upregulating m6A modification and THBS1 expression. Targeting the HOTAIR/WTAP/THBS1 pathway may prevent or treat PCO.

Maxillary molar distalization with clear aligner therapy and infrazygomatic temporary skeletal anchorage devices

American Journal of Orthodontics and Dentofacial Orthopedics · 2025-10-17

Usage of Silver Nanoparticles in Orthodontic Appliances

Materials · 2025-12-29

Orthodontic treatment, offering significant benefits for oral function and facial aesthetics, is in high demand among both adolescent and adult populations. Orthodontic appliances pose challenges for maintaining oral hygiene and increase the risk of dental and periodontal diseases. With advances in dental materials and the use of nanoparticles, a significant amount of research has focused on modifying orthodontic appliances with nanoparticles to reduce bacterial adhesion and biofilm formation. Silver nanoparticles are one of the most popular antibacterial materials in medical research. This article presents current evidence on silver nanoparticle-incorporated orthodontic appliances, including brackets, molar bands, archwires, elastomeric ligatures, mini-implants, and acrylic retainers. Silver nanoparticles and modified silver nanoparticles exhibit robust antibacterial activity when applied to the surfaces of orthodontic appliances. However, there are exceptions in which, on a few orthodontic appliances, the silver nanoparticle incorporation actually increased biofilm formation. Moreover, a silver nanoparticle incorporation may introduce adverse effects, such as cytotoxicity, and increase surface roughness. It is also worth noting that most of the studies were conducted in vitro. Long-term clinical studies are necessary to evaluate the stability, safety, and clinical efficacy of silver nanoparticle-incorporated orthodontic appliances under real-world conditions.