About

Clint Stalnecker is an Assistant Professor in the Department of Biochemistry and Biophysics at the University of North Carolina at Chapel Hill. His research focuses on signal transduction networks and therapeutics, utilizing multi-omic approaches such as metabolomics, proteomics, transcriptomics, genetic screens, and drug screens to understand cellular signaling events. He investigates how signaling networks reprogram in response to targeted therapies to develop clinically actionable combination therapy strategies. Dr. Stalnecker has received several awards and honors, including the Forbeck Scholar award in 2025, the Donald F. Reinhold Memorial Lecturer honor in 2025, and the Ruth L. Kirschstein Fellowship Award from NIH in 2019.

Research topics

• Biology
• Cell biology
• Computer Science
• Genetics
• Cancer research
• Medicine
• Internal medicine
• Computational biology
• Pharmacology
• Biochemistry

Selected publications

• Figure S1 page2 from Combination Therapies with CDK4/6 Inhibitors to Treat <i>KRAS-</i>Mutant Pancreatic Cancer

  2025-11-24

  articleOpen access

  <p>Figure S1 page2</p>

  PublisherDOI

• Figure S5 page2 from Combination Therapies with CDK4/6 Inhibitors to Treat <i>KRAS-</i>Mutant Pancreatic Cancer

  2025-11-24

  articleOpen access

  <p>Figure S5 page2</p>

  PublisherDOI

• Supplementary Data and Materials from Combination Therapies with CDK4/6 Inhibitors to Treat <i>KRAS-</i>Mutant Pancreatic Cancer

  2025-11-24

  articleOpen access

  <p>Supplementary Data and Materials</p>

  PublisherDOI

• Figure S2 page1 from Combination Therapies with CDK4/6 Inhibitors to Treat <i>KRAS-</i>Mutant Pancreatic Cancer

  2025-11-24

  articleOpen access

  <p>Figure S2 page1</p>

  PublisherDOI

• Figure S5 page2 from Combination Therapies with CDK4/6 Inhibitors to Treat <i>KRAS-</i>Mutant Pancreatic Cancer

  2025-11-24

  articleOpen access

  <p>Figure S5 page2</p>

  PublisherDOI

• Figure S2 page2 from Combination Therapies with CDK4/6 Inhibitors to Treat <i>KRAS-</i>Mutant Pancreatic Cancer

  2025-11-24

  articleOpen access

  <p>Figure S2 page2</p>

  PublisherDOI

• Figure S1 page3 from Combination Therapies with CDK4/6 Inhibitors to Treat <i>KRAS-</i>Mutant Pancreatic Cancer

  2025-11-24

  articleOpen access

  <p>Figure S1 page3</p>

  PublisherDOI

• Figure S3 page1 from Combination Therapies with CDK4/6 Inhibitors to Treat <i>KRAS-</i>Mutant Pancreatic Cancer

  2025-11-24

  articleOpen access

  <p>Figure S3 page1</p>

  PublisherDOI

• Figure S7 page1 from Combination Therapies with CDK4/6 Inhibitors to Treat <i>KRAS-</i>Mutant Pancreatic Cancer

  2025-11-24

  articleOpen access

  <p>Figure S7 page1</p>

  PublisherDOI

• Figure S7 page3 from Combination Therapies with CDK4/6 Inhibitors to Treat <i>KRAS-</i>Mutant Pancreatic Cancer

  2025-11-24

  articleOpen access

  <p>Figure S7 page3</p>

  PublisherDOI

Recent grants

• Defining the contributions of WT RAS in RAS-mutant lung cancer

  NIH · $193k · 2019–2022

• The mitochondrial enzyme glutaminase: Its role in cancer cell metabolism

  NIH · $80k · 2014–2016

Frequent coauthors

• Channing J. Der

  University of North Carolina at Chapel Hill

  131 shared

• Adrienne D. Cox

  University of North Carolina at Chapel Hill

  124 shared

• Jennifer E. Klomp

  University of North Carolina at Chapel Hill

  102 shared

• Kirsten L. Bryant

  University of North Carolina at Chapel Hill

  88 shared

• Andrew M. Waters

  University of Cincinnati

  87 shared

• Runying Yang

  University of North Carolina at Chapel Hill

  84 shared

• Bjoern Papke

  Charité - Universitätsmedizin Berlin

  76 shared

• Craig M. Goodwin

  University of North Carolina at Chapel Hill

  75 shared

Labs

• UNC Biochemistry and BiophysicsPI

Education

• Ph.D., Chemistry and Chemical Biology

  Cornell University

  2016

• B.S., Chemistry and Biochemistry

  Albright College

  2009

Awards & honors

• Forbeck Scholar, William Guy Forbeck Research Foundation, 20…
• The Donald F. Reinhold, PhD ’44 Memorial Chemistry and Bioch…
• Keynote speaker, Thermo Proteomics Symposium, UNC-Chapel Hil…
• Developmental Research Award, UNC Pancreatic Cancer SPORE, 2…
• Ruth L. Kirschstein Fellowship Award, NIH, 2019