
Craig Hirschberg
· Chair, Department of EndodonticsVerifiedRutgers University · Endodontics
Active 2013–2024
About
Craig Hirschberg is the Chair of the Department of Endodontics at Rutgers School of Dental Medicine. The page does not provide additional details about his research focus, background, or key contributions.
Research topics
- Medicine
- Dentistry
- Orthodontics
- Information Retrieval
- Computer Science
- Internal medicine
- Materials science
- Endocrinology
- Anatomy
- Mathematics
- Genetics
- Biology
- Surgery
- Database
- Neuroscience
- Intensive care medicine
Selected publications
Journal of Endodontics · 2024-01-29
paratextOpen accessJournal of Endodontics · 2023-12-12
paratextOpen accessJournal of Endodontics · 2023-02-25
paratextOpen accessJournal of Dental Education · 2023-05-29 · 3 citations
articleOpen accessThe fifth biennial Advanced Dental Education Summit was organized by the ADEA Council on Advanced Education Programs. With a focus on "Resident selection, assessment, and management," the summit aimed to discuss best practices for selecting, assessing, and managing advanced education residents. Expert presentations covered the resident's journey from interview to graduation, emphasizing strategies for supporting resident wellness, success, and evaluation. The summit provided recommendations, including the incorporation of psychosocial assessments in the selection process, early recognition of behavioral issues, clearly defining clinical competencies, and creating a culture of wellness through supportive policies and structures.
Journal of Endodontics · 2023-09-01
paratextOpen accessJournal of Endodontics · 2021-05-24
paratextOpen accessThe Journal of Gene Medicine · 2021 · 15 citations
- Genetics
- Biology
- Neuroscience
BACKGROUND: Genetic variation in the catechol-O-methyltransferase (COMT) gene is associated with sensitivity to both acute experimental pain and chronic pain conditions. Four single nucleotide polymorphisms (SNPs) have traditionally been used to infer three common haplotypes designated as low, average and high pain sensitivity and are reported to affect both COMT enzymatic activity and pain sensitivity. One mechanism that may partly explain individual differences in sensitivity to pain is conditioned pain modulation (CPM). We hypothesized that variation in CPM may have a genetic basis. METHODS: We evaluated CPM in 77 healthy pain-free Caucasian subjects by applying repeated mechanical stimuli to the dominant forearm using 26-g von Frey filament as the test stimulus with immersion of the non-dominant hand in hot water as the conditioning stimulus. We assayed COMT SNP genotypes by the TaqMan method using DNA extracted from saliva. RESULTS: met) was not associated with individual differences in CPM. However, CPM was associated with COMT low pain sensitivity haplotypes under an additive model (p = 0.004) and the effect was independent of gender. CONCLUSIONS: We show that, although four SNPs are used to infer COMT haplotypes, the low pain sensitivity haplotype is determined by SNP rs6269 (located in the 5' regulatory region of COMT), suggesting that inherited variation in gene expression may underlie individual differences in pain modulation. Analysis of 13 global populations revealed that the COMT low pain sensitivity haplotype varies in frequency from 13% to 44% and showed that two SNPs are sufficient to distinguish all COMT haplotypes in most populations.
Journal of Endodontics · 2021-03-23
paratextOpen accessJournal of Endodontics · 2021-07-20
articleOpen accessJournal of Endodontics · 2021-07-20
paratextOpen access
Frequent coauthors
- 13 shared
Gary Hartwell
Smith College
- 11 shared
Junad Khan
Eastman Chemical Company (United States)
- 11 shared
Eli Eliav
Eastman Chemical Company (United States)
- 10 shared
Cibele Nasri‐Heir
- 10 shared
Ching‐Yu Huang
Kean University
- 10 shared
Fengshen Kuo
- 10 shared
Olga A. Korczeniewska
- 10 shared
Scott R. Diehl
Rutgers, The State University of New Jersey
Labs
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