David S. Seres, M.D.
Columbia University · American Language Program
Active 1981–2024
About
David S. Seres, M.D. is a faculty affiliate and advisory board member at Columbia University School of Professional Studies. He serves as the Director of Medical Nutrition and is a Professor of Medicine in the Institute of Human Nutrition at Columbia University Medical Center. His professional focus involves medical nutrition, contributing to the academic and clinical advancement of nutrition science within the university. His roles indicate a leadership position in medical nutrition, emphasizing his expertise and contributions to the field.
Research topics
- Internal medicine
- Medicine
- Intensive care medicine
- Pediatrics
- Environmental health
- Family medicine
Selected publications
Nutrition in Clinical Practice · 2022 · 18 citations
Senior authorCorresponding- Medicine
- Internal medicine
- Pediatrics
BACKGROUND: Heart failure (HF) is highly prevalent, whereas malnutrition is generally associated with poorer hospital outcomes, and it is not uncommon in patients with HF. Prior studies of the effect of malnutrition on HF outcomes are limited in size and quality. This study aims to elucidate the association between malnutrition and hospital length of stay (LOS), mortality, and discharge destination in patients with HF. METHODS: This is a retrospective review of medical records for inpatients admitted with a primary diagnosis of HF in 2018. Patients with HF and severe protein-calorie malnutrition were compared with those without malnutrition. A two-sided t-test was conducted between patients who have HF with and without malnutrition on hospital outcomes. Multivariate logistic regression was developed to identify potential predictors of malnutrition. A propensity score was calculated for each patient and matched cases (malnutrition with nonmalnutrition) to balance covariates and reduce bias. RESULTS: For N = 7079, the median age was 75 years, with 15.79% having severe malnutrition. Overall mortality was 5.57% (394 deceased) . There were significant associations between malnutrition and both mortality (relative risk, 2.22; P < 0.001) and LOS (10 vs 5 days, P < 0.001) in patients with HF. Significantly fewer patients with malnutrition were discharged home (odds ratio, 0.41; P < 0.001). CONCLUSION: Patients with HF and malnutrition have higher risk for mortality, increased LOS in the hospital, and decreased chance of being discharged home. Continued study of this population is required to better predict which patients with malnutrition will respond to nutrition interventions.
Nature Medicine · 2021 · 4960 citations
- Medicine
- Intensive care medicine
- Internal medicine
ASPEN Consensus Recommendations for Refeeding Syndrome
Nutrition in Clinical Practice · 2020 · 466 citations
- Medicine
- Intensive care medicine
- Family medicine
INTRODUCTION: In the spring of 2017, the American Society for Parenteral and Enteral Nutrition (ASPEN) Parenteral Nutrition Safety Committee and the Clinical Practice Committee convened an interprofessional task force to develop consensus recommendations for identifying patients with or at risk for refeeding syndrome (RS) and for avoiding and managing the condition. This report provides narrative review and consensus recommendations in hospitalized adult and pediatric populations. METHODS: Because of the variation in definitions and methods reported in the literature, a consensus process was developed. Subgroups of authors investigated specific issues through literature review. Summaries were presented to the entire group for discussion via email and teleconferences. Each section was then compiled into a master document, several revisions of which were reviewed by the committee. FINDINGS/RECOMMENDATIONS: This group proposes a new clinical definition, and criteria for stratifying risk with treatment and screening strategies. The authors propose that RS diagnostic criteria be stratified as follows: a decrease in any 1, 2, or 3 of serum phosphorus, potassium, and/or magnesium levels by 10%-20% (mild), 20%-30% (moderate), or >30% and/or organ dysfunction resulting from a decrease in any of these and/or due to thiamin deficiency (severe), occurring within 5 days of reintroduction of calories. CONCLUSIONS: These consensus recommendations are intended to provide guidance regarding recognizing risk and identifying, stratifying, avoiding and managing RS. This consensus definition is additionally intended to be used as a basis for further research into the incidence, consequences, pathophysiology, avoidance, and treatment of RS.
Frequent coauthors
- 50 shared
Neeraj Badjatia
University of Maryland, Baltimore
- 47 shared
Jan Claassen
NewYork–Presbyterian Hospital
- 46 shared
Stephan A. Mayer
Westchester Medical Center
- 39 shared
E. Sander Connolly
- 37 shared
Wahida Karmally
Columbia University Irving Medical Center
- 37 shared
Eoin Slattery
Health Service Executive
- 26 shared
Serge Cremers
Columbia University Irving Medical Center
- 23 shared
Alexander P. Maxwell
Queen's University Belfast
Awards & honors
- Columbia SPS CUNY Fellowship
- Columbia HBCU Fellowship Program
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