About

Dr. David I. Suster is an Associate Professor in the Department of Pathology, Immunology and Laboratory Medicine at Rutgers New Jersey Medical School. He earned his M.D. from Tulane University School of Medicine in 2014 and completed his pathology residency at Beth Israel Deaconess Medical Center, Harvard Medical School. Following his residency, he completed a fellowship at Massachusetts General Hospital, Harvard Medical School, specializing in bone and soft tissue pathology as well as pulmonary pathology. His areas of interest include bone and soft tissue pathology and pulmonary pathology. Dr. Suster has contributed to the field through numerous publications, including research on cartilaginous lesions of bone, sarcomatoid renal cell carcinoma, osteoblastoma, spindle cell liposarcoma, and thymic carcinomas, among others. His work involves detailed diagnostic and research efforts in these areas, reflecting his expertise in complex pathological diagnoses and research in soft tissue and pulmonary diseases.

Research topics

• Medicine
• Pathology
• Biology
• Biochemistry
• Genetics
• Molecular biology
• Endocrinology
• Virology
• Immunology
• Cell biology

Selected publications

• 80 Osteosarcoma in Adults Over 40: A Clinicopathologic Study of 58 Patients

  Laboratory Investigation · 2026-03-01

  article1st authorCorresponding
  PublisherDOI

• 1655 Lung Adenocarcinoma with Papillolepidic Growth Pattern: Study of 12 Cases Supporting the In-Situ Nature of the Papillary Component

  Laboratory Investigation · 2026-03-01

  articleOpen accessSenior author
  PublisherOA PDFDOI

• 1654 Malignant Thymic Neoplasms with Basaloid Features: Clinicopathologic Study of 19 Cases with a Reevaluation of So-called “Basaloid Carcinoma” of the Thymus

  Laboratory Investigation · 2026-03-01

  article1st authorCorresponding
  PublisherDOI

• Chondroblastoma with prominent secondary aneurysmal bone cyst-like changes: The role of H3.3 K36 M

  Human Pathology · 2026-04-27

  article1st authorCorresponding
  PublisherDOI

• 81 Spectrum of Histologic Changes and the Role of Residual Viable Tumor Burden in Treated Osteosarcoma: A Clinicopathologic Study of 112 Cases

  Laboratory Investigation · 2026-03-01

  articleSenior author
  PublisherDOI

• Immunohistochemical evaluation of ERG expression in soft tissue tumours: a tissue microarray study of 489 cases

  Journal of Clinical Pathology · 2025-08-22

  article1st authorCorresponding

  AIMS: ) in a large number of soft tissue neoplasms using a tissue microarray technique. METHODS: 489 cases of soft tissue neoplasms, including benign and malignant entities, were collected from the files of the respective institutions and constructed into tissue microarrays. Tissue microarrays were stained for ERG immunohistochemistry using two antibodies, EP111 and EPR3864. RESULTS: A total of 25 cases (5.1%) were identified that were positive for ERG using the monoclonal antibody EP111 and 15 cases (3%) using the monoclonal antibody EPR3864, including rhabdomyosarcoma, peripheral nerve sheath tumours, synovial sarcoma, myxofibrosarcoma, epithelioid sarcoma, dermatofibrosarcoma protuberans, low-grade fibromyxoid sarcoma, nodular fasciitis and dedifferentiated liposarcoma. The most consistently stained tumours included synovial sarcoma, rhabdomyosarcoma and benign and malignant peripheral nerve sheath tumours. Various other fibroblastic proliferations, including dermatofibrosarcoma protuberans, myxofibrosarcoma, low-grade fibromyxoid sarcoma and nodular fasciitis, also showed positive staining in a small fraction of cases. One case of dedifferentiated liposarcoma showed nuclear positivity for ERG, and one case of epithelioid sarcoma was also positive. CONCLUSIONS: This study supports the value of ERG as a highly sensitive and specific marker for the diagnosis of vascular neoplasms but also demonstrates rare cases of aberrant staining and underscores the need to assess soft tissue tumours using a panel of stains and interpret the results of immunohistochemistry in the appropriate histological and clinical context.

  PublisherDOI

• Pseudoneoplastic Fat Atrophy of Intra-Abdominal Sites

  The American Journal of Surgical Pathology · 2025-12-17

  article1st authorCorresponding

  Patients undergoing periods of starvation or malnutrition may develop degenerative and/or atrophic changes of various organs. These findings may manifest histologically and may cause confusion when first encountered, raising a differential that includes benign and malignant tumor entities. Herein, we report 16 cases of incidentally identified degenerative changes within abdominal-site fatty tissues that caused diagnostic difficulties. The patients were 11 males and 5 females, aged from 1 day to 82 years (mean: 58 years). The degenerative changes were all incidentally identified within adipose tissue of the abdominal cavity or adjacent to organs contained within the abdominal cavity in procedures done for unrelated reasons such as cancer, infection, or perforation. Cases were identified in the colon (n=6), small intestine (n=4), omentum (n=3), inguinal hernia sac (n=1), peritoneum (n=1), and retroperitoneal soft tissue (n=1). Patients had variable past medical histories with multiple comorbidities. Ten patients presented with some form of malnutrition and/or cachexia. Histologically, the lesions demonstrated lobules of atrophic-appearing fat with small signet-ring-like adipocytes that were sometimes bilobed. The nodules varied in size and were characterized in some cases by a variably myxoid stromal background, often with a prominent delicate capillary network. Immunohistochemistry was performed and was uniformly positive for S100 protein and negative for cytokeratins. The lesions were generally recognized as degenerative, but various differential diagnoses proposed at the time of sign-out included signet-ring cell carcinoma, liposarcoma, and vascular lesions, among others. Nomenclature to describe this phenomenon has been inconsistent in the literature, and thus, we suggest the term "pseudoneoplastic fat atrophy."

  PublisherDOI

• 49 Expanding the Clinicopathologic Spectrum of Sarcomas with EWSR1::SSX Fusions

  Laboratory Investigation · 2025-03-01 · 1 citations

  articleOpen access
  PublisherOA PDFDOI

• Ossifying Spindled and Epithelioid Tumor: A Novel Soft Tissue Tumor

  Modern Pathology · 2025-07-16 · 5 citations

  article
  PublisherDOI

• Path to Health Equity and Improved Outcomes through Inclusive Sex and Gender Data Collection in Genomic Testing

  Journal of Molecular Diagnostics · 2025-05-15

  review
  PublisherDOI

Frequent coauthors

• Saul Suster

  Medical College of Wisconsin

  88 shared

• Alexander C. Mackinnon

  University of Alabama at Birmingham

  42 shared

• Gerard J. Nuovo

  The Ohio State University Wexner Medical Center

  21 shared

• Germán Pihán

  20 shared

• John Gross

  Johns Hopkins Medicine

  20 shared

• Natali Ronen

  Medical College of Wisconsin

  19 shared

• Esmerina Tili

  The Ohio State University Wexner Medical Center

  18 shared

• Haider A. Mejbel

  Emory University

  18 shared

Education

• M.D.

  Tulane University School of Medicine

  2014

• Other, bone and soft tissue and pulmonary pathology

  Massachusetts General Hospital, Harvard Medical School

• Other, pathology

  Beth Israel Deaconess Medical Center, Harvard Medical School