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Nova · Professor Researcher · re-ranking top 20…

Alberto Pochettino

· Associate Professor of Surgery at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia and the Pennsylvania HospitalVerified

University of Pennsylvania · Rehabilitation Medicine

Active 1974–2026

h-index62
Citations14.3k
Papers36180 last 5y
Funding
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Research signals

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Research topics

  • Medicine
  • Cardiology
  • Surgery
  • Internal medicine
  • Anesthesia

Selected publications

  • Long-term Outcomes of Open Thoracoabdominal Aortic Repair in Connective Tissue Disease Patients: A 12-year Institutional Experience

    Journal of Vascular Surgery · 2026-03-23

    article
  • Ascending aorta to iliac artery bypass in coral reef aorta with multidrug resistant hypertension and worsening renal function

    Journal of Vascular Surgery Cases and Innovative Techniques · 2026-01-08

    articleOpen access

    Coral reef aorta is a rare condition characterized by heavily calcified atherosclerotic disease that involves the juxtarenal aorta, leading to potentially life-threatening complications (congestive heart failure, refractory hypertension, and visceral or limb ischemia). Here, we report the case of an elderly woman with resistant hypertension and worsening kidney function with a solitary right kidney, who underwent successful open surgical repair using the ascending aorta as an inflow source to a bypass graft to the renal, mesenteric and iliac arteries. This approach provides an effective and durable option for difficult coral reef aorta cases not amenable to other less invasive approaches.

  • Reoperations after the Ross procedure: Techniques, complexity, and outcomes

    JTCVS structural and endovascular. · 2026-01-18

    articleOpen accessSenior author
  • Type B Aortic Dissection in Patients Aged 30 Years or Younger: A Retrospective Multicentre Study

    European Journal of Cardio-Thoracic Surgery · 2025-12-12

    article

    OBJECTIVES: Type B aortic dissection (TBAD) is rare in patients aged ≤30 years, and data on this population remain limited. This study aimed to characterize the underlying aetiology, and outcomes of invasively treated young patients with TBAD, with a focus on the impact of heritable thoracic aortic disease (HTAD). METHODS: A retrospective multicentre analysis was conducted across 19 international aortic centres, including 139 patients aged ≤30 years with TBAD. Patients with chronic TBAD (n = 42) were excluded for the final analysis. The cohort was classified as uncomplicated (n = 86) or complicated (n = 53) TBAD. Clinical, radiologic, intraoperative, and postoperative data were collected using standardized forms. Outcomes were compared between subgroups defined by TBAD complexity, HTAD status, and surgical strategy. Kaplan-Meier and Andersen-Gill analyses were used for survival and recurrent aortic intervention, respectively. RESULTS: Mean follow-up time was 6.5 years. HTAD was identified in 57% of patients. Most presented with uncomplicated TBAD (62%), while high-risk uncomplicated cases were uncommon. Endovascular repair was predominant in complicated TBAD, while open repair was more frequent in uncomplicated cases. Early mortality was low (n = 3), and mid-term survival was excellent across all subgroups. HTAD was a significant predictor of recurrent aortic interventions (HR = 3.3, P = .004). No significant differences were observed in survival or reintervention rates between uncomplicated and complicated TBAD or between operative strategies. CONCLUSIONS: In young patients, TBAD predominantly occurs in the context of HTAD. Both open and endovascular repair are associated with excellent early outcomes and mid-term survival. However, HTAD remains a significant predictor of recurrent aortic interventions.

  • Changes in ejection fraction after coronary artery bypass grafting for ischemic cardiomyopathy: Impact on survival and determinants of improvement

    Journal of Thoracic and Cardiovascular Surgery · 2025-10-30 · 1 citations

    article
  • A Novel Preoperative Risk Prediction Model of Non-home Discharge After Open Thoracoabdominal Aortic Aneurysm Repair

    Journal of Vascular Surgery · 2025-05-23

    articleOpen access
  • Aortoesophageal fistula: Long-term survival with aggressive multidisciplinary management

    JTCVS Techniques · 2025-09-25

    articleOpen access

    Objective: Aortoesophageal fistula (AoEF) is a rare but complex problem that carries high mortality. This study describes our institutional experience with the management of AoEF. Methods: There were 17 patients with AoEF who were managed in our center (2005-2023). Medical records were reviewed for baseline characteristics, history of esophageal or aortic disease, diagnostic evaluation, surgical treatment, and follow-up. Overall survival (OS) was analyzed using the Kaplan-Meier method and log rank tests. Results: < .001). Conclusions: Management of AoEF is complex. However, aggressive multidisciplinary intervention with definitive esophageal and aortic repairs can result in good long-term survival in selected patients.

  • Partial diaphragm division is associated with decreased ventilator support after open thoracoabdominal aortic repair

    Journal of Vascular Surgery · 2025-08-22

    article
  • Treatment Trends and Outcomes of Endovascular versus Open Thoracoabdominal Aortic Aneurysm Repair – A Single-center Comparative Cohort Study

    Annals of Surgery · 2025-07-25 · 2 citations

    article

    OBJECTIVE: To evaluate treatment trends and compare outcomes following fenestrated-branched endovascular aortic repair (FB-EVAR) versus open surgical repair (OSR) of thoracoabdominal aortic aneurysms (TAAA). BACKGROUND: FB-EVAR has been increasingly utilized as a less invasive alternative to OSR for treatment of TAAAs. METHODS: We studied patients who underwent elective FB-EVAR or OSR of TAAAs (2008-2020), since the initiation of an Advanced Endovascular Aortic Program. Primary endpoints were early major adverse events (MAE) and early and late all-cause mortality. Propensity score overlap weighting analysis was performed to adjust for measured confounders between groups. RESULTS: There were 357 (70.8%) patients treated by FB-EVAR and 147 (29.2%) with OSR. The use of FB-EVAR increased from 16.7% in 2008 to >80% since 2017 (P<0.001). Incidences of early MAEs were 25.8% and 49.0%, respectively; early mortality rates for FB-EVAR and OSR were 2.5% and 6.8%, respectively. In the weighted cohort, FB-EVAR patients had decreased early MAEs (weight-adjusted odds ratio [aOR], 0.28; 95% confidence interval [CI], 0.18-0.41; P<0.001) and mortality (aOR, 0.35; 95% CI, 0.17-0.73; P=0.005) versus OSR patients. Five-year survival estimates were 52.2% (95% CI, 45.2-60.4%) and 78.0% (95% CI, 70.6-86.2%), respectively. In the weighted cohort, there was no significant difference in late survival between groups (weight-adjusted hazard ratio, 1.33; 95% CI, 0.74-2.39; P=0.34). CONCLUSIONS: This study confirmed the change in practice from OSR to FB-EVAR for treatment of TAAAs over the past decade. Incidences of early MAEs and mortality were lower with FB-EVAR, with no significant difference in late survival in the weighted cohort.

  • Partial Diaphragm Division Is Associated With Decreased Ventilator Support After Open Thoracoabdominal Aortic Repair

    Journal of Vascular Surgery · 2025-03-17

    article

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