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Hung S. Ho, M.D., F.A.C.S.

Hung S. Ho, M.D., F.A.C.S.

· Assistant Professor of SurgeryVerified

University of California, Davis · Surgery

Active 1986–2026

h-index35
Citations4.9k
Papers11630 last 5y
Funding
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About

Hung S. Ho, M.D., F.A.C.S., is a faculty member in the Department of Surgery at UC Davis Health, specializing in areas related to surgery. His specific research focus, background, and key contributions are not detailed in the provided page text. The page lists him among the faculty involved in the department's various surgical specialties, but does not include a detailed biography or description of his research or professional achievements.

Research topics

  • Psychology
  • Medicine
  • Computer Science
  • Social psychology
  • Nursing
  • Virology
  • Artificial Intelligence
  • Family medicine
  • Applied psychology
  • Advertising
  • Medical emergency
  • Internet privacy
  • Mathematics
  • Environmental health
  • Business

Selected publications

  • Comparative Efficacy of Microfluidics and Density Gradient Centrifugation for Sperm Preparation in IVF: A Randomized Controlled Trial

    JBRA · 2026-01-01

    articleOpen accessSenior author

    OBJECTIVE: To compare the effectiveness of microfluidic sperm sorting (MC) and traditional density gradient centrifugation (DGC) in reducing sperm DNA fragmentation index (DFI) and evaluate their impact on clinical outcomes in IVF cycles. METHODS: In this randomized controlled trial, 119 couples undergoing IVF were allocated to either the MC or DGC group. Sperm DNA fragmentation was assessed before and after preparation. Primary outcomes included live birth rate and DFI reduction. Secondary outcomes were sperm quality parameters, fertilization rate, embryo development, and pregnancy outcomes. Subgroup analysis was conducted based on initial DFI levels (<15% vs. ≥15%). RESULTS: The MC group demonstrated significantly greater and more consistent DFI reduction, particularly in samples with high baseline DFI (≥15%), compared to the DGC group. Although the number of oocytes retrieved was higher in the MC group, no significant differences were observed between groups in fertilization rate, Day-2 embryo quality, clinical pregnancy, ongoing pregnancy, or live birth rates. Subgroup analysis also showed no significant differences in outcomes based on baseline DFI levels. CONCLUSIONS: Microfluidics is an effective method for reducing sperm DNA fragmentation, particularly in samples with high DFI. However, this improvement does not necessarily guarantee better clinical outcomes in IVF. Baseline sperm DNA fragmentation index (DFI) may still act as an independent prognostic factor influencing IVF success, regardless of the sperm preparation method used.

  • FSHR GENETIC VARIANTS AS PREDICTIVE MARKERS OF OVARIAN RESPONSE IN IVF PATIENTS WITH DIMINISHED OVARIAN RESERVE

    Fertility and Sterility · 2025-12-01

    articleOpen access
  • The Impact of FSHR Polymorphisms (rs6165 and rs6166) on Ovarian Response to Stimulation in Infertile Women with Diminished Ovarian Reserve

    The Application of Clinical Genetics · 2025-07-01 · 3 citations

    articleOpen accessSenior author

    Background: Diminished ovarian reserve (DOR) remains a significant challenge in IVF, as it is closely associated with poor ovarian response. Beyond well-established predictive of ovarian response, genetic polymorphisms in the FSH receptor (FSHR) gene rs6165 and rs6166 have been reported as potential markers. Purpose: Evaluating the expression of FSHR rs6165 and rs6166 in DOR patients and their impact on ovarian response to stimulation. Materials and Methods: This prospective cross-sectional included 79 DOR patients (AMH < 1.2 ng/mL and/or AFC < 5) undergoing IVF treatment at the National Hospital of Obstetrics and Gynecology, Vietnam. GnRH antagonist protocol was applied, using alpha follitropin with individualized dosages combined with clomiphene citrate, followed by dual-trigger ovulation induction. FSHR rs6165 and rs6166 were genotyped by Next-Generation Sequencing (NGS) assays, with Sanger sequencing for validation. Ovarian response was assessed based on follicular development and oocyte retrieval. Results: The overall prevalence of the rs6165 and rs6166 polymorphisms was 10.1% (8/79), with strong linkage disequilibrium observed between the two loci (OR = 490, p < 0.0001). No significant differences in age, AMH, baseline FSH, and AFC were found in all genotypes (AA, AG, GG) of rs6165 and rs6166. In the rs6165 dominant model, patients with G alleles (AG/GG) had lower total oocyte retrieval, FOI and FORT than the AA genotype. In rs6166 codominant, dominant, and recessive models, the GG phenotype retrieved fewer oocytes (p1 = 0.02, p2 = 0.03, p3 = 0.01). FORT was significantly lower in G allele carriers (AG/GG) than AA (p = 0.04). Conclusion: In the diminished ovarian reserve patients, FSHR rs6165 and rs6166 were associated with ovarian response to stimulation in IVF treatment. Specifically, the presence of G alleles in both rs6165 and rs6166 was correlated with reduced oocyte retrieval, independent of baseline ovarian reserve markers.

  • Parasitic Myoma: A Rare Complication of Laparoscopic Myomectomy

    Cureus · 2025-01-30 · 1 citations

    articleOpen access1st authorCorresponding

    The occurrence of a parasitic myoma is an unusual condition and it is traditionally thought to be a variant of pedunculated subserosal myoma that has become separated from the uterus and received alternative blood supply. However, the prevalence of laparoscopic surgery might have brought a new type of parasitic myoma named iatrogenic parasitic myoma. This type of parasitic myoma raises the question of whether it should be considered as a long-term complication of laparoscopic myomectomy. This report aims to present a case of parasitic myoma in a 38-year-old woman who underwent laparoscopic myomectomy using a morcellator. Due to the prevalence of laparoscopic myomectomies and the risk of spreading unsuspected leiomyosarcoma with morcellation, this case highlights the need for in-bag containment morcellation to extract specimens. At the same time, a careful inspection and washing of the abdominopelvic cavity at the end of the surgery should be performed to minimize the complication of open power morcellation.

  • Technical differences between Hinotori and da Vinci robotic systems in the context of radical prostatectomy

    European Urology Open Science · 2025-09-01

    articleOpen accessSenior author
  • Evaluation of the Follitropin Delta and Clomiphene Citrate Combination in Low Prognosis Women Undergoing In Vitro Fertilization: A Retrospective Study

    Clinical and Experimental Obstetrics & Gynecology · 2025-11-26

    articleOpen access

    Background: In assisted reproductive technology, particularly in vitro fertilization (IVF), optimizing ovarian stimulation protocols using individualized recombinant follicle-stimulating hormone (FSH) preparations, such as follitropin delta, has gained attention for its potential to improve treatment outcomes and reduce the risk of ovarian hyperstimulation syndrome (OHSS). This study aimed to evaluate the efficacy of combining follitropin delta and clomiphene citrate (CC) in women with a suboptimal response to ovarian stimulation using follitropin alpha during IVF. Methods: A retrospective study was conducted in women undergoing two consecutive IVF cycles at the Military Institute of Clinical Embryology and Histology, Vietnam. The first cycle utilized follitropin alpha, followed by a second cycle with follitropin delta plus CC. Embryological outcomes were assessed, including the number of stimulated follicles, the number of oocytes retrieved, and embryo quality at cleavage and blastocyst stages. A mixed-effects model with a negative binomial or Poisson distribution was applied to analyze repeated measurements within the same individual. Results: A total of 57 women were included in the final analysis. Following a suboptimal response to follitropin alpha, ovarian stimulation with follitropin delta plus CC resulted in a significant increase in the number of total day 3 embryos (p = 0.018), total day 5–6 embryos (p = 0.017), and good-quality blastocysts (p = 0.028). The number of stimulated follicles also showed a trend toward improvement (p = 0.043). No significant differences were observed in the number of oocytes retrieved or metaphase II (MII) oocytes. Conclusions: In women who previously demonstrated a suboptimal ovarian response, follitropin delta combined with CC was associated with improved embryological outcomes compared to conventional follitropins. These findings suggest that combining follitropin delta and CC may optimise ovarian response and embryo quality in this patient population. Further studies are warranted to confirm these results and assess the impact of this combination treatment on clinical pregnancy and live birth rates.

  • Toxic Exposures in Children: A Review of Emergency Department Transfers to a Tertiary Pediatric Hospital

    Journal of the American College of Emergency Physicians Open · 2025-03-13 · 1 citations

    reviewOpen access

    Objectives: Pediatric poisonings are a common emergency department (ED) presentation. In some instances, the first hospital may not have the capability to manage a pediatric patient beyond initial stabilization, requiring transfer to a tertiary children's hospital. This study aims to describe the clinical characteristics and outcomes of pediatric transfers following various xenobiotic exposures. Methods: We performed a retrospective analysis of patients ≤18 years transferred to a tertiary children's hospital for any intentional or unintentional xenobiotic exposure between July 1, 2021 and June 30, 2023. An electronic data query was performed using specific keywords, and then, medical record reviews were conducted by a team of emergency medicine physicians and medical toxicologists. Information regarding exposure, interventions, and disposition was collected. Results: A total of 544 patients were identified, and 167 were included in this analysis. The median age was 15 years (IQR: 5, 17). Of the 167 patients, 134 (80.2%) were admitted to the children's hospital. Acetaminophen was the most common exposure (n = 37, 22.2%), followed by polysubstance (n = 24, 14.3%) and tetrahydrocannabinol (n = 13, 7.8%). Intravenous normal saline bolus was the most common initial intervention. Forty-eight (28.8%) patients were directly admitted from the first ED, and 119 patients were ED to ED transfers. Of those, 86 (72.3%) patients were ultimately admitted from the second ED to an inpatient unit. Conclusion: Most transferred patients were admitted, making these transfers clinically indicated and an appropriate use of resources. When comparing characteristics of admitted versus discharged patients, no clear difference beyond age was noted.

  • 1. OUTCOMES OF OUTPATIENT HYSTEROSCOPY IN INFERTILE WOMEN AT THE NATIONAL HOSPITAL OF OBSTETRICS AND GYNECOLOGY

    Tạp chí Y học Cộng đồng · 2025-06-26

    articleOpen access

    Introduction: Outpatient hysteroscopy is an effective and safe diagnostic and therapeutic method for detecting intrauterine lesions in infertile women, especially in those with suggestive abnormalities or previous assisted reproductive failures. Objectives: To evaluate the outcomes of outpatient hysteroscopy in infertile patients at the National Hospital of Obstetrics and Gynecology. Methods: A descriptive study (combining retrospective and prospective data) was conducted on 149 infertile patients undergoing outpatient hysteroscopy at the National Center for Reproductive Assistance, National Hospital of Obstetrics and Gynecology, from November 2024 to April 2025. Results: The mean age of the study population was 36.1 ± 5.2 years, with 64.4% of patients aged over 35. The median duration of infertility was 3 years (range: 1–28 years). Most patients had no prior intrauterine interventions (81.2%) and no history of uterine surgery (77.9%). Ultrasound detected intrauterine cavity abnormalities in 53.7% of cases (80/149), whereas hysterosalpingography (HSG) identified abnormalities in only 40% (14/35). The indication for diagnostic hysteroscopy is about 40.3%, including consecutive failed preimplantation (35.6%) and recurrent miscarriage (4.7%). Outpatient hysteroscopy confirmed intrauterine pathology in 81.2% of cases, predominantly endometrial polyps (46.3%), endometritis (16.1%), and intrauterine adhesions (18.1%). Interventions during hysteroscopy included polypectomy (46.3%), adhesiolysis of the uterine cavity (18.1%), submucosal myomectomy (1.3%), and endometrial biopsy (2.7%). The median procedure time was 8 minutes (range: 3–30 minutes), with no complications reported. The median volume of saline used was 800 ml (range: 60–3000 ml). Ultrasound showed strong agreement with hysteroscopy in diagnosing polyps (Kappa = 0.824; p &lt; 0.001), whereas HSG demonstrated poor agreement in detecting both polyps and intrauterine adhesions (Kappa &lt; 0.2; p &lt; 0.05). Conclusion: Office hysteroscopy is an effective tool for detecting intrauterine lesions in infertile patients. It allows both diagnosis and intervention in a short duration and is safe for the patient.

  • Hyperkinetic Biliary Dyskinesia: An Underrecognized Problem With Good Surgical Outcomes After Cholecystectomy

    Cureus · 2024-06-26 · 4 citations

    articleOpen access

    Introduction While surgical indications for symptomatic cholelithiasis and biliary hypokinesia are clear, hyperkinetic biliary dyskinesia (HBD) is an underrecognized condition with poorly defined symptomology and management guidelines. HBD is typically defined as a gallbladder ejection fraction (EF) ≥ 80% on a hepatobiliary iminodiacetic acid (HIDA) scan. We aimed to identify the prevalence and radiographic reporting of HBD, physician referral patterns, and clinical outcomes following cholecystectomy. Methods A retrospective cohort study of patients with HIDA scans completed over 21 years at our tertiary care hospital was performed. Demographics, symptomatology, referral patterns, and operative data were collected. HBD was defined as HIDA EF ≥80%. Patients with HBD who underwent cholecystectomy were analyzed. ANOVA and chi-square tests were used to compare variables among patients with or without symptom improvement using Statistical Product and Service Solutions (SPSS; IBM SPSS Statistics for Windows, Armonk, NY). Results Of 1,997 patients (73% female, mean age 51.7 years) who had HIDA scans with reported EF, 730 (36.6%) had an EF≥80%. Only 13.7% of HIDA scans with EF≥80% were reported as hyperkinetic, and the rest are “normal”. Cholecystectomy was performed in 57 (7.8%) patients with EF≥80%, most being elective (89.5%) and all minimally invasive. Primary care physicians (PCPs) referred most elective cases to surgery (61.4%). The median time from HIDA to cholecystectomy was 146 days. Chronic cholecystitis was common in pathology (82.5%), while 38.6% had cholelithiasis. Overall, 53 patients (93.0%) reported symptom improvement at a median follow-up of 17.0 days. Patients without improvement had a higher prevalence of chronic gastrointestinal conditions (p&lt;0.05), but not significantly more cholelithiasis, cholecystitis, time to surgery, or elective surgery status. Conclusions HBD is common but often underdiagnosed and thus likely underrecognized by treating physicians. Most HBD patients benefit from cholecystectomy, regardless of cholelithiasis. Patients with persistent symptoms after cholecystectomy may have confounding gastrointestinal diagnoses. Increased awareness among radiologists, referring PCPs, gastroenterologists, and surgeons about HBD and postoperative outcomes is needed to ensure that HBD is adequately treated.

  • Epinephrine induced digital ischemia treated with phentolamine

    Visual Journal of Emergency Medicine · 2024-04-01

    article1st author

Frequent coauthors

Labs

  • Department of Surgery, UC Davis HealthPI

Awards & honors

  • Earl F. Wolfman, Jr. MD and Lois J. Wolfman, Endowed Profess…
  • Certificate of Appreciation; Thai-Binh Medical University, T…
  • US Faculty Scholar, Vietnam Education Foundation, 2009
  • Gunther Schlag Memorial Research Award, 1999
  • Young Investigator Award, International Association of Pancr…
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