About

Jennifer JooYeon Lee is an Assistant Professor in the Administrative Sciences at Boston University Metropolitan College, where she also serves as the Coordinator of Global Marketing Management. Her research adopts a multidisciplinary approach to marketing and information economics, focusing on understanding information asymmetry in markets and organizations, as well as consumer decision-making processes in digital markets. She emphasizes developing externally valid research to bridge the gap between academic theory and practical application. Professor Lee is actively involved in scholarly activities, serving as an associate editor of the Journal of Consumer Marketing and participating in professional organizations such as the American Marketing Association, the Academy of Marketing Science, GAMMA, and the Society for Marketing Advances. Her teaching expertise includes digital marketing, platform business, retailing, marketing strategy, quantitative marketing, and marketing research. She teaches graduate courses such as Digital Platforms and Quantitative Marketing, Ecommerce, Marketing Analytics, and Innovative Marketing Techniques, with a focus on practical, real-world applications like web-based simulation projects that enhance student engagement and skills relevant to the industry.

Research topics

• Medicine
• Internal medicine
• Immunology
• Surgery
• Gastroenterology
• Biology
• Molecular biology
• Dermatology
• Genetics
• Bioinformatics
• Ophthalmology
• Oncology
• Microbiology

Selected publications

• 26-CCC-16463-ACC A RARE CASE OF PULMONARY ARTERY STENOSIS FROM ANCA-ASSOCIATED VASCULITIS: THE DIAGNOSTIC ROLE OF CARDIAC MRI

  Journal of the American College of Cardiology · 2026-03-27

  article
  PublisherDOI

• Clarifying the conceptual dimensions of representation in neuroscience

  Nature reviews. Neuroscience · 2026-03-20 · 1 citations

  preprintOpen access
  PublisherOA PDFDOI

• Mesenchymal stem cells derived from human bone marrow ameliorate monosodium urate crystal-induced inflammation

  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2026-02-11

  articleSenior authorCorresponding
  PublisherDOI

• Macrophage activation syndrome in systemic lupus erythematosus: risk factors and outcomes

  Clinical Rheumatology · 2026-04-08

  article
  PublisherDOI

• Clinical value of salivary gland ultrasonography in evaluating secretory function, disease activity, and lymphoma risk factors in primary Sjögren’s syndrome

  Clinical Rheumatology · 2025-03-04 · 7 citations

  article
  PublisherDOI

• Recruitment rates, retention rates, and follow-up completion in a Brief Intervention and Contact trial for suicidal behavior: a feasibility study

  Pilot and Feasibility Studies · 2025-04-16 · 2 citations

  articleOpen access

  BACKGROUND: Suicide is a serious public health concern for which there are limited evidence-based interventions being employed. This feasibility study administered a Brief Intervention and Contact (BIC) trial adopted from the WHO Multisite Intervention Study on Suicidal Behaviors (SUPRE-MISS) and followed participants after they had been discharged from the inpatient hospital setting. AIMS: To assess the recruitment and retention rates, follow-up visit completion, barriers to recruitment and retention, resources needed of employing this study, and data completion. METHODS: Eligible participants were recruited from psychiatric inpatient settings, in Hamilton, Ontario. Adults with suicidal behavior were randomly allocated to BIC (intervention) plus treatment as usual (TAU) or treatment as usual (control) and were followed for 6 months. The intervention arm completed 9 follow-up points during the 6-month follow-up period post-discharge. Calculation of recruitment and retention rates and associated statistical analyses were completed using SPSS version 25. RESULTS: A total of 154 participants were approached during the 8-month recruitment period, 60 participants were enrolled resulting in a recruitment rate of 7.625 participants per month. A total of 61 participants were recruited, with 1 duplicate. The retention rate was 47.5% for the recruited participants at the end of the study. CONCLUSIONS: Few suicide-based follow up interventions assess the feasibility of conducting the study. Retention was low for this study; however, participants outlined reasons for withdrawal that are consistent with other research areas related to mental health. Findings from this study will help inform suicide research on the barriers and challenges to participant recruitment and retention. TRIAL REGISTRATION: NCT03825354, Registered January 30 th, 2019, ClinicalTrial.gov; https://clinicaltrials.gov/study/NCT03825354?cond=suicide&term=brief%20intervention%20and%20contact&rank=6.

  PublisherOA PDFDOI

• Efficacy and safety of home-based transcranial direct current stimulation as adjunct treatment for cognitive improvement in major depressive disorder: A double-blind, randomized, multi-site clinical trial

  European Psychiatry · 2025-01-01 · 3 citations

  articleOpen access

  Abstract Background Transcranial direct current stimulation (tDCS) is a promising treatment for major depressive disorder (MDD). This study evaluated its antidepressant and cognitive effects as a safe, effective, home-based therapy for MDD. Methods This double-blind, sham-controlled, randomized trial divided participants into low-intensity (1 mA, n = 47), high-intensity (2 mA, n = 49), and sham ( n = 45) groups, receiving 42 daily tDCS sessions, including weekends and holidays, targeting the dorsolateral prefrontal cortex for 30 minutes. Assessments were conducted at baseline and weeks 2, 4, and 6. The primary outcome was cognitive improvement assessed by changes in total accuracy on the 2-back test from baseline to week 6. Secondary outcomes included changes in depressive symptoms (HAM-D), anxiety (HAM-A), and quality of life (QLES). Adverse events were monitored. This trial was registered with ClinicalTrials.gov (NCT04709952). Results In the tDCS study, of 141 participants (102 [72.3%] women; mean age 35.7 years, standard deviation 12.7), 95 completed the trial. Mean changes in the total accuracy scores from baseline to week 6 were compared across the three groups using an F -test. Linear mixed-effects models examined the interaction of group and time. Results showed no significant differences among groups in cognitive or depressive outcomes at week 6. Active groups experienced more mild adverse events compared to sham but had similar rates of severe adverse events and dropout. Conclusions Home-based tDCS for MDD demonstrated no evidence of effectiveness but was safe and well-tolerated. Further research is needed to address the technical limitations, evaluate broader cognitive functions, and extend durations to evaluate its therapeutic potential.

  PublisherOA PDFDOI

• Dietary Menaquinone-9 Supplementation Does Not Influence Bone Tissue Quality or Bone Mineral Density in Mice

  Current Developments in Nutrition · 2025-05-01

  articleOpen access

  Objectives: Vitamin K has been implicated in skeletal health because vitamin K-dependent proteins are present in bone. While there are multiple forms of vitamin K, most research has focused on phylloquinone, which is found mainly in plant-based foods, and menaquinone-4 (MK4), which is a metabolite of phylloquinone. However, there are additional forms of vitamin K that are bacterially produced that may influence bone health but have not yet been studied extensively. Herein, we evaluated the effects of menaquinone-9 (MK9), a bacterially produced form of vitamin K on bone tissue quality and bone mineral density (BMD) in young mice.

  PublisherDOI

• 0299 Sleep Timing and Social Jet Lag Are Associated with Circadian Gene Expression: A Cross-sectional Study in Mexico City Adolescents

  SLEEP · 2025-05-01

  articleOpen access

  Abstract Introduction Circadian disruption has been linked to adverse metabolic health, potentially mediated through altered expression of circadian genes. Adolescents are particularly susceptible to circadian disruptors, such as delayed sleep onset and social jetlag. This study of adolescents during peri-puberty investigated associations between circadian disruption and circadian gene expression, independent of sleep duration, and potential sex differences in the associations. Methods The analytic sample included 203 adolescents (96 boys, 107 girls) from the ELEMENT longitudinal cohort in Mexico City. Sleep was assessed via 7-day wrist actigraphy, and a fasted blood sample was collected during a study visit between 8:00 AM and 12:00 PM. Sleep midpoint was calculated as the midpoint between bed and wake times, and social jetlag as the difference in sleep midpoint on weekends versus weekdays. RNA was isolated from blood leukocytes, and RNA sequencing was performed to determine the relative expression of genes. We conducted differential gene expression analysis, in relation to weekday sleep midpoint and social jetlag, for 12 core clock genes using the DESeq2 package (R), adjusting for sleep duration and other potential confounders. A Bonferroni-corrected statistical significance (0.05/12 genes) was considered. Results Participants had a median age of 14 years (interquartile range: 12–16). Later sleep midpoint (per 1-hour increase) was associated with reduced mid-morning expression of four circadian genes: RORA (log2 fold change [LFC]: -0.190; P value: 0.001), RORC (LFC: -0.147; P value: 0.039), CLOCK (LFC: -0.141; P value: 0.019), and NR1D2 (LFC: -0.093; P value: 0.029). In sex-stratified analysis, later sleep midpoint was significantly associated with lower RORA expression in girls only (LFC: -0.255; P value: 0.002). Greater social jetlag was linked to increased expression of PER1 (LFC: 0.275; P value: 0.017) in girls, but no associations were found in boys or the combined sample. The associations with RORA met a more stringent Bonferroni-corrected statistical significance (P< 0.004). Conclusion Later weekday sleep midpoint and greater social jetlag were associated with altered expression of some core clock genes collected in mid-morning, particularly among adolescent females. Future studies are needed to evaluate the potential impact of differential clock gene expression, especially for RORA, on cardiometabolic health. Support (if any) K01HL151673

  PublisherOA PDFDOI

• Dietary Menaquinone-9 Supplementation Does Not Influence Bone Tissue Quality or Bone Mineral Density in Mice

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-02-02 · 1 citations

  preprintOpen access

  ABSTRACT Vitamin K has been implicated in skeletal health because vitamin K-dependent proteins are present in bone. While there are multiple forms of vitamin K, most research has focused on phylloquinone, which is found mainly in plant-based foods, and its metabolite menaquinone-4 (MK4). However, there are additional forms of vitamin K that are bacterially produced that appear to influence bone health but have not yet been studied extensively. Herein, we evaluated the effects of menaquinone-9 (MK9), a bacterially produced form of vitamin K on bone tissue quality and density in young mice. Four-week-old male (n=32) and female (n=32) C57BL/6 mice were supplemented with 0.06 mg/kg diet or 2.1 mg/kg diet of MK9 for 12 weeks. During week 11, a sub-group of mice (n=7/sex/group) received daily deuterium-labeled MK9 to trace its metabolic fate in bone. Liver MK4 and MK9 were significantly higher in mice fed 2.1 mg MK9/kg compared to those receiving 0.06 mg MK9/kg, regardless of sex (all p ≤ 0.017). MK4 was the only vitamin K form detected in bone, with 63-67% of skeletal MK4 in mice fed 2.1 mg MK9/kg derived from deuterium-labeled MK9. Femoral tissue strength, maximum bending moment, section modulus, and bone mineral density did not differ significantly across diet groups in either sex (all p≥0.083). Cross-sectional area (p=0.003) and moment of inertia (p=0.001) were lower in female mice receiving 2.1 mg MK9/kg compared to those receiving 0.06 mg MK9/kg, but no differences were found in male mice. Higher bone MK4 concentrations did not correlate with higher bone tissue quality or density. Despite dietary MK9 being a dietary precursor to MK4 in bone, dietary MK9 supplementation did not affect bone tissue quality or bone mineral density. Lay summary Most research about vitamin K and bone health has focused on phylloquinone, the plant-based vitamin K form, and its metabolite menaquinone-4. Because interest in bacterially produced forms of vitamin K, which are abundant in the intestinal microbiome, is growing, we evaluated the effect of menaquinone-9 (a bacterially-produced form of vitamin K) on skeletal health. We supplemented mice with low and high doses of menaquinone-9 and also used stable-isotope labeled menaquinone-9 to trace its conversion to menaquinone-4 in bone. We found menaquinone-9 served as a precursor to menaquinone-4 in bone, but menaquinone-9 supplementation did not improve bone health.

  PublisherOA PDFDOI

Frequent coauthors

• Sung‐Hwan Park

  Seoul St. Mary's Hospital

  325 shared

• Seung‐Ki Kwok

  Seoul St. Mary's Hospital

  258 shared

• Ji Hyeon Ju

  Catholic University of Korea

  187 shared

• Stephan Pohl

  101 shared

• David L. Barack

  101 shared

• Edgar Y. Walker

  University of Washington

  101 shared

• Ned Block

  New York University

  101 shared

• Rachel N. Denison

  Boston University

  101 shared

Awards & honors

• Mary Kay Doctoral Dissertation Proposal Award at AMS
• Best Paper Awards at SMA and ICBE
• Award for Excellence in Research at SUNY Binghamton
• Best Paper Award at the International Conference on Business…
• Best Paper in Marketing Strategy Track at Society for Market…