
Jonathan Novak
· Associate ProfessorVerifiedUniversity of California, San Diego · Mathematics
Active 1938–2026
About
I am a professor of mathematics at UC San Diego, where my activities include research and teaching. I also serve on the editorial board of the open access journal Algebraic Combinatorics.
Research topics
- Statistical physics
- Mathematics
- Physics
- Mathematical physics
- Pure mathematics
Selected publications
arXiv (Cornell University) · 2026-03-31
preprintOpen access1st authorCorrespondingIn this paper, we introduce and study random Schur measures whose parameters are sampled from the Circular Unitary Ensemble. We show that Schur measures with CUE disorder exhibit behavior reminiscent of spin glasses.
ArXiv.org · 2026-03-31
articleOpen access1st authorCorrespondingIn this paper, we introduce and study random Schur measures whose parameters are sampled from the Circular Unitary Ensemble. We show that Schur measures with CUE disorder exhibit behavior reminiscent of spin glasses.
Clinical Pharmacology in Drug Development · 2025-04-30 · 3 citations
articleOpen accessAbstract RBN‐3143 is an inhibitor of PARP14 in development for inflammatory diseases. Multiple assessments were conducted to evaluate the clinical pharmacology properties of RBN‐3134. A randomized, double‐blind, placebo‐controlled study assigned healthy volunteers (HVs) to single ascending doses (SADs) (25‐1000 mg) or multiple ascending doses (MADs) (150, 300, and 500 mg twice daily [BID] for 14 days) of RBN‐3143 or placebo. An open‐label, randomized, 3‐period, cross‐over study evaluated the effects of food and pantoprazole (40 mg once daily [QD]) on the pharmacokinetics of RBN‐3143 (500 mg), and a pharmacokinetic drug–drug interaction study with oral midazolam (2 mg) determined whether RBN‐3143 (300 mg BID for 14 days) is an inducer of cytochrome P4503A4 (CYP3A4). The most common treatment‐related treatment‐emergent adverse events in subjects taking RBN‐3143 were headache, nausea, vomiting, and elevated serum creatinine. In the SAD, RBN‐3143 C max and AUC inf increased with dose, and T max was 2 hours. RBN‐3143 was cleared from plasma with an apparent terminal half‐life ranging from 3 to 11 hours. In the MAD, C max and AUC inf increased 1.5‐ and 1.6‐fold, respectively, following 14 days of 150, 300, and 500 mg BID dosing. Dosing of RBN‐3143 with food resulted in higher C max and AUC inf ratios of 1.74 and 1.42, respectively. Coadministration with pantoprazole did not impact RBN‐3143 exposure. RBN‐3143 was an inducer of CYP3A4 in most but not all subjects, with mean midazolam C max and AUC inf ratios of 0.92 and 0.88, respectively. The clinical pharmacology properties of RBN‐3143 in HVs support further development for inflammatory diseases.
Quasimodular Asymptotics of Spherical Integrals
ArXiv.org · 2025-02-19
preprintOpen access1st authorCorrespondingWe show that the spherical integral of the Circular Unitary Ensemble converges in expectation to Euler's generating function for integer partitions, and that subleading corrections to this high-dimensional limit are quasimodular forms.
Hypergeometric Functions of Random Matrices and Quasimodular Forms
arXiv (Cornell University) · 2024-10-05
preprintOpen access1st authorCorrespondingHypergeometric functions of complex matrices were introduced by James in multivariate statistics. These special functions play many roles in random matrix theory. The main goal of this paper is to suggest a new use for them as holomorphic observables of the Circular Unitary Ensemble. We analyze the high-dimensional behavior of the expected derivatives of these random analytic functions, and show that they admit asymptotic expansions which can be described in terms of quasimodular forms, giving an apparently new connection between the CUE and number theory.
On the 2D Yang-Mills/Hurwitz Correspondence
arXiv (Cornell University) · 2024-01-01 · 1 citations
preprintOpen access1st authorCorrespondingIn this paper, we show that in the large $N$ limit two-dimensional Yang-Mills theory with $U(N)$ gauge group becomes mixed Hurwitz theory, in the sense that the $1/N$ expansion of the chiral partition function receives contributions from both classical and monotone Hurwitz theory for all but finitely many compact orientable spacetimes.
Increasing subsequences and Kronecker coefficients
Proceedings of symposia in pure mathematics · 2024-08-06 · 2 citations
other1st authorCorrespondingISID1096 - The PARP14 inhibitor RBN-3143 suppresses skin inflammation in preclinical models
2023-05-05 · 1 citations
preprintNotices of the American Mathematical Society · 2022-04-14 · 2 citations
preprintOpen accessSenior authorThis is a short introduction to Weingarten Calculus. Weingarten Calculus is a method to compute the joint moments of matrix variables distributed according to the Haar measure of compact groups.
Topological Expansion of Oscillatory BGW and HCIZ Integrals at Strong Coupling
arXiv (Cornell University) · 2022-03-21
preprintOpen access1st authorCorrespondingWe prove that the BGW and HCIZ integrals admit large N topological expansions for complex coupling and complex external fields, provided the coupling is sufficiently strong. The expansion coefficients are holomorphic functions which are genus-specific generating functions for the monotone single and double Hurwitz numbers, respectively.
Recent grants
Invariant Ensembles of Random Matrices: New Techniques, New Horizons
NSF · $150k · 2018–2022
Frequent coauthors
- 12 shared
Sho Matsumoto
Kyushu University
- 9 shared
Mathieu Guay-Paquet
Université du Québec à Montréal
- 9 shared
I. P. Goulden
University of Waterloo
- 6 shared
C. Benoît
Kyoto University
- 3 shared
Maciej Dołęga
- 3 shared
Alice Guionnet
Unité de Mathématiques Pures et Appliquées
- 3 shared
Colin McSwiggen
- 3 shared
Piotr Śniady
Awards & honors
- Hellman Fellowship
- Lattimer Fellowship
- Simons-CRM Scholar
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