About

Larry P. Frohman, MD, is a Professor of Ophthalmology and Neurology at Rutgers New Jersey Medical School, where he also serves as Vice Chair of the Department of Ophthalmology. He is a graduate of Swarthmore College and the University of Pennsylvania School of Medicine, completing his residency in Ophthalmology at NYU-Bellevue and specialized neuro-ophthalmology training under Dr. Mark Kupersmith. Dr. Frohman practices neuro-ophthalmology with a focus on unexplained visual loss, vasculitis/autoimmune disease, and sarcoidosis of the visual system. He has held numerous leadership roles, including EVP of the North American Neuro-Ophthalmology Society (NANOS), where he has served on its Board for 16 years, and has been its President and Chair of its Educational and Practice Management Committees. He has also contributed significantly to the American Academy of Ophthalmology as a Councilor and as the initial Chair of the Neuro-ophthalmology/Orbit Section of the practicing ophthalmologist’s curriculum. Dr. Frohman has been recognized with awards such as the Senior Honor Award from AAO and has been named in various Best Doctors publications. His research interests include autoimmune diseases affecting the visual system, optic neuritis, pseudotumor cerebri, and systemic diseases like sarcoidosis and vasculitis. He has contributed to the field through clinical practice, leadership, and scholarly publications.

Research topics

• Immunology
• Pathology
• Surgery
• Ophthalmology
• Medicine
• Dermatology

Selected publications

• Management of Binocular Diplopia With Prism Incorporated Ocular Impression-Based Scleral Lenses With and Without Wavefront-Guided Optics

  Eye & Contact Lens Science & Clinical Practice · 2026-05-01

  article

  OBJECTIVE: The purpose of this study was to report the efficacy of prism-incorporated impression-based scleral lenses (pibSL) in the management of binocular diplopia. METHODS: This case series includes seven patients with various etiologies of binocular diplopia, including congenital and acquired conditions, that were managed with pibSLs. Of the seven patients, two had corneal irregularity. Visual acuity (VA), diplopia resolution, and subjective patient reports on comfort and cosmetics were assessed. Wavefront-guided (wfg) optics were incorporated in select cases where poor visual quality was reported. RESULTS: All patients experienced resolution of diplopia with VA improving to 20/20 or better with pibSLs. Wfg optics reduced residual higher-order aberrations, resulting in subjective improvement in vision quality and balanced VA. Patients reported high levels of satisfaction with pibSL. CONCLUSIONS: PibSLs are an effective, well-tolerated alternative to traditional prism spectacles for managing binocular diplopia and can address multiple comorbidities. The addition of wfg optics further improved visual quality in patients with complex visual needs.

  PublisherDOI

• From Observation to Prediction: Machine Learning Analysis of Progression of Visual loss in Nonarteritic Anterior Ischemic Optic Neuropathy

  American Journal of Ophthalmology · 2026-02-11

  article
  PublisherDOI

• More Than Meets the Eye: A Case of Delayed Sequential Bilateral Vision Loss

  Journal of Neuro-Ophthalmology · 2025-12-01

  articleSenior author
  PublisherDOI

• A Challenging Case of Progressive Bilateral Optic Neuropathy

  Journal of Neuro-Ophthalmology · 2025-10-23

  articleSenior authorCorresponding
  PublisherDOI

• Uveal Effusion Syndrome Temporally Associated with Primary COVID-19 Infection

  Seminars in Ophthalmology · 2024-07-23

  article

  PURPOSE: To report a case of uveal effusion syndrome in association with primary COVID-19 infection to share our experience and insight in diagnosing and managing this unique case. CASE PRESENTATION: A 56-year-old woman presented with angle closure glaucoma of both eyes. Further examination and imaging revealed the etiology to be related to bilateral uveal effusions and choroidal thickening in the setting of recent COVID-19 infection. The patient's glaucoma was managed with bilateral iridotomies and medical therapy, while the precipitating uveal effusions resolved with treatment on oral steroids. CONCLUSION: While uveal effusion syndrome has been associated with COVID-19 vaccination, it has not yet been reported after primary infection. Recognition of this rare phenomenon will allow for better diagnosis and treatment in future cases.

  PublisherDOI

• Do Refractive Errors Cause Headaches?

  2024-05-28

  book-chapter1st authorCorresponding

  For many years, the question as to whether headaches can be caused by refractive errors (that require glasses) has been debated. The question is still not fully answered. One problem is that if you ask patients if they have headaches, the answer is commonly yes. In a study by Whittington 1 of more than 1400 consecutive patients presenting for refraction, 45% reported headache. In such studies, it is likely that the use of “headache” overlaps with the concept of asthenopia, which may be a nonspecific malaise of the eyes with use. To further analyze if headache may truly be caused by refractive error, we must first define what we mean by “headache.”

  PublisherDOI

• Opinions ∙ Informational Power and the Origins of German Privacy Law

  European Data Protection Law Review · 2024-01-01 · 2 citations

  articleOpen access1st authorCorresponding
  PublisherOA PDFDOI

• Progressive Blurry Vision and Hearing Loss in a Young Male Patient

  Journal of Neuro-Ophthalmology · 2024-11-25

  articleSenior authorCorresponding
  PublisherDOI

• OCT retinal nerve fiber layer thickness differentiates acute optic neuritis from MOG antibody-associated disease and Multiple Sclerosis

  Multiple Sclerosis and Related Disorders · 2022 · 86 citations

  • Medicine
  • Ophthalmology
  • Surgery
  PublisherOA PDFDOI

• Acute Onset of Diplopia in an Uncontrolled Diabetic

  Journal of Neuro-Ophthalmology · 2022-01-21

  articleSenior author

  Gill, Aditya S. MD; Turbin, Roger MD; Frohman, Larry MDEditor(s): Frohman, Larry MD Author Information

  PublisherDOI

Frequent coauthors

• Roger E. Turbin

  Rutgers, The State University of New Jersey

  115 shared

• Leonard Bielory

  Center for Discovery

  76 shared

• Mark J. Kupersmith

  Icahn School of Medicine at Mount Sinai

  35 shared

• Leo Wolansky

  University of Connecticut

  34 shared

• Bonnie Bruce

  Emory University

  28 shared

• Floyd A. Warren

  Culham Science Centre

  27 shared

• Kathleen B. Digre

  26 shared

• Paul D. Langer

  Rutgers, The State University of New Jersey

  24 shared

Education

• B.A.

  Swarthmore College

  1976

• M.D.

  University of Pennsylvania, School of Medicine

  1980

Awards & honors

• Senior Honor Award (American Academy of Ophthalmology)
• Two Secretariat awards (American Academy of Ophthalmology)