About

Lloyd D. Petty is an academic professional and practicing endocrinologist affiliated with the University of Utah Health. His clinical interests encompass a wide range of endocrine disorders, including diabetes, osteoporosis, and thyroid disease. He is board certified by the American Board of Internal Medicine with a subspecialty in Endocrinology, Diabetes & Metabolism. Dr. Petty is recognized for his thoroughness, knowledge, and compassionate approach to patient care, often providing detailed explanations and engaging in discussions about treatment options. His expertise is highly regarded by patients, who frequently commend his listening skills, kindness, and ability to offer the latest treatments. His professional focus includes improving health through innovation, research, and clinical excellence, making him a trusted provider for individuals with complex endocrine conditions.

Research topics

• Internal medicine
• Medicine
• Pediatrics
• Surgery
• Endocrinology
• Gastroenterology

Selected publications

• Risk Factors for Fragility Fractures in Chronic Lymphocytic Leukemia

  Cureus · 2024 · 4 citations

  1st authorCorresponding
  • Medicine
  • Internal medicine
  • Endocrinology

  -scores not being in the osteoporotic range. Increased awareness to screen and treat vertebral FFs in people with CLL is needed.

  PublisherOA PDFDOI

• Graves’ Disease With Initial Presentation of Thyrotoxic Periodic Paralysis

  Cureus · 2023 · 4 citations

  1st authorCorresponding
  • Medicine
  • Pediatrics
  • Surgery

  Graves' disease is a common cause of hyperthyroidism. However, thyrotoxic periodic paralysis (TPP) is a rare complication of Graves' disease and is characterized by episodes of muscle weakness and hypokalemia in the setting of thyrotoxicosis. Episodic weakness and paralysis can be the first manifestation of Graves' disease with TPP despite lacking classic symptoms of hyperthyroidism and can be precipitated by risk factors such as a high carbohydrate diet and strenuous exercise. Although TPP is reversible with correction of hypokalemia and thyrotoxicosis, its uncommon presentation can lead to delay in diagnosis and treatment. Here, we describe a case of a 24-year-old Thai male who presented with proximal muscle weakness that progressed to frequent falls and inability to ambulate over the course of three days. He was found to have severe hypokalemia and diagnosed with TPP from underlying Graves' disease. He was treated with cautious replacement of potassium, a beta blocker, and methimazole to reverse thyrotoxicosis. He regained his ability to ambulate, and his weakness resolved after hypokalemia was corrected. He did not have a reoccurrence of muscle weakness the following 12 months after discharge by continuing treatment with methimazole. The varied clinical manifestations of TPP can make diagnosis challenging, but early recognition and treatment can prevent severe complications of this potentially life-threatening condition.

  PublisherOA PDFDOI

• ODP090 Fragility Fractures and Osteoporosis Screening in Patients with Chronic Lymphocytic Leukemia

  Journal of the Endocrine Society · 2022 · 3 citations

  1st authorCorresponding
  • Medicine
  • Internal medicine
  • Gastroenterology

  Abstract Chronic lymphocytic leukemia (CLL) and osteoporosis are diseases of older adults with high prevalence rates. CLL infiltrates the bone marrow, increasing bone resorption and demineralization which contribute to the pathophysiology of osteoporosis. Despite this, there are limited clinical data describing the association of CLL with osteoporosis and fracture risk. We hypothesized that osteoporosis and fragility fractures (FF) are common in patients with CLL. The Huntsman Cancer Institute (HCI) has a CLL database which includes all patients diagnosed with CLL since January 1, 2000 and received care at the HCI. Patients included were identified from the CLL database with ICD-9 and 10 codes associated with osteopenia, osteoporosis and/or presence of a FF. Of the 57 patients included, 67% were female (n=38) with a mean age of 69 ± 10 years and 93% Caucasian. 60% (n=34) had RAI stage of 0-1 with genetic changes noted as follows: Del(13q) 46% (n=26), Del(17p) 7% (n=4), Del(11q) 5% (n=3), and Trisomy 12 14% (n=8). IGVH mutation was present in 31.6% of patients (n=18). 47% (n=25) of patients were treated with chemotherapy, of which Rituximab (n=14), Bendamustine (n=7), Cyclophosphamide (n=5), and Ibrutinib (n=5) were the most frequently used. 58.5% (n=32) had a history of FF, with 84% occurring in the spine (n=27/32). Assessment for Vitamin D deficiency and hyperparathyroidism were performed in 54% (n=31) and 21% (n=12) of the cohort respectively. Even though every patient in the study either had a diagnosis of osteoporosis by ICD code or FF, only 44% (n=25) of patients had an available DXA scan for our review, and only 31% (n=18) received treatment for osteoporosis. Of those with a DXA, the worst T score was in the right femoral neck (T score -1.9, IQR -1.5 to -2.5) with 44% (n=14/32) either having T scores in the normal or osteopenic range. Interestingly, FF was associated with higher T scores in the spine (FF spine T score -1. 0±1.5 vs no FF T score -2.2±0.8, p=0. 03). Clinical factors associated with FF were male sex (83% men vs 46% women, p<0. 01) and positive smoking history (93% smokers vs 46% non-smokers, p<0. 01). Use of chemotherapy and hip T scores were not associated with FF. The data from our study suggests that patients with CLL are predisposed to axial fragility fractures despite non-osteoporotic T scores. In addition, osteoporosis screening with DXA is under-utilized in the CLL population, despite meeting age-appropriate screening guidelines. Increased awareness and screening for axial fragility fractures, especially in men and smokers, should be recommended in the long term follow up of patients with CLL. Further study is needed to understand the pathophysiology of osteoporosis and FF in patients with CLL to develop improved methods for prevention of these morbid fractures. Presentation: No date and time listed

  PublisherOA PDFDOI

• Utilization of bilateral percutaneous microwave ablation of the adrenal glands in ectopic Cushing's syndrome

  Radiology Case Reports · 2022-09-30

  articleOpen access1st author

  Ectopic Cushing's syndrome (CS) is rare and difficult to cure when the source is elusive. Medical management is complex and often times contraindicated in the medically complex patient. We present a complicated case of ectopic CS where bilateral percutaneous microwave ablation (MWA) of the adrenal glands successfully cured hypercortisolism when surgery and medical therapies were contraindicated. A 71-year-old male was diagnosed with ectopic CS after adrenocorticotropic hormone-dependent hypercortisolism persisted after hypophysectomy despite a positive gradient of >3 on inferior petrosal sinus sampling. An ectopic source was not identified. Surgery and medical therapies were contraindicated due to comorbidities and drug interactions. Bilateral MWA of the adrenal glands was performed. Postprocedurally cortisol levels declined and the patient was clinically adrenally insufficient at 6 months. Bilateral MWA of the adrenal glands can prove to be an effective treatment option for ectopic CS when surgical resection and medical therapies are ineffective or contraindicated.

  PublisherDOI

• Abstract #1038809: Hypokalemic Periodic Paralysis as Initial Presentation for Graves’ Disease

  Endocrine Practice · 2021 · 1 citations

  1st authorCorresponding
  • Medicine
  • Pediatrics
  • Internal medicine
  PublisherDOI

• Abstract #1038815: Bilateral Adrenal Ablation in patient with Persistent Cushing's

  Endocrine Practice · 2021-05-28

  article1st authorCorresponding
  PublisherDOI

• Gastric Outlet Obstruction Caused by Gravid Uterus

  ACG Case Reports Journal · 2020-02-01

  articleOpen access

  CASE REPORT Intestinal obstruction in pregnancy has an incidence ranging from 1 in 1,500 to 1 in 66,500 and occurs most commonly during the third trimester when the gravid uterus rises into the abdomen.1 The most common causes for intestinal obstruction in pregnancy include adhesions from previous surgeries or cesarean births, intussusception, malignancy, and hernias.2 We present a case of gravid uterus causing gastric outlet obstruction without any of the earlier mentioned risk factors. A 34-year-old woman, G9P6026 at 35 weeks, with no significant medical or surgical history presented with a 2-day history of nausea, dry heaving, and dull epigastric pain. She was not on any medications and denied the use of any nonsteroidal anti-inflammatory drugs. Physical examination was significant for distended abdomen with a gravid uterus along with mild tenderness to palpation in the epigastric region. Laboratory evaluation was unremarkable. Abdominal computed tomography obtained in the emergency department showed a large gravid uterus resulting in compression of the distal stomach and duodenum leading to marked gastric distension, consistent with gastric outlet obstruction (Figure 1). No other lesion or source of obstruction was noted. The patient was managed conservatively with nasogastric tube decompression with significant improvement in her symptoms. She was discharged after 2 days on a full liquid diet, which she tolerated well, and her symptoms completely resolved after the delivery of her baby 4 weeks later. An esophagogastroduodenoscopy was performed a few months later, which was normal including random gastric biopsies.Figure 1.: Abdominal computed tomography showing a large gravid uterus.DISCLOSURES Author contributions: S. Paleti and L. Petty wrote the manuscript and revised the manuscript for intellectual content. T. Rustagi approved the final version and is the article guarantor. Financial disclosure: None to report. Informed consent was obtained for this case report.

  PublisherDOI

• Case report: Pulmonary sequestration in an adult

  Radiology Case Reports · 2017-11-22 · 26 citations

  articleOpen access1st authorCorresponding

  Pulmonary sequestration is a rare congenital malformation that is uncommonly diagnosed during adulthood. Pulmonary sequestrations can manifest with variable presentations. It can remain asymptomatic or present with more severe symptoms such as hemoptysis and recurrent pneumonia. Diagnosis can be confirmed with computed tomography angiogram or angiography. Treatment with embolization of the afferent artery and surgical removal of the pulmonary sequestration generally has good outcomes. We report a case of a 43-year-old man who presented with recurrent pneumonia and left-sided back pain and was eventually diagnosed with pulmonary sequestration.

  PublisherDOI

• A Fairy Tale with a Hairy Tail

  Digestive Diseases and Sciences · 2017-11-08 · 1 citations

  article
  PublisherDOI

• RELATIONSHIP BETWEEN HAND/FOOT LATERALITY AND EYE DOMINANCE

  NSUWorks (Nova Southeastern University) · 2016-01-01

  article1st authorCorresponding

  Objective. This study was conducted to determine if there is an association between hand dominance, foot dominance, and eye dominance. Background. Lateral dominance describes the asymmetrical preference and function of the human body. It is most commonly used when referring to handedness, that is to say, whether an individual prefers to use his or her right hand or left hand. However, it is unclear whether or not there is a correlation between hand preference, and the preference of other parts of the body, such as feet and eyes. Eye dominance, although researched extensively in the past, still remains a theoretical puzzle. Methods. Data was collected via an online survey sent to members of the general population (n=73, 33 males and 44 females). Questions about the participants included age, gender, ethnicity, and preferences in hand and foot laterality. Eye dominance was determined by asking participants to perform the Miles Test. Results. Most of the participants were right hand dominant (87.5%), while fewer participants were left handed (12.5%). The majority of right hand dominant people were right foot dominant (98%), and the majority of left hand dominant people were left foot dominant (67%). On the other hand, most people were right eye dominant whether they were left handed or right handed. Conclusion. A statistically significant relationship was found between hand and foot dominance (p<0.001), however, the same was not found to be true between hand and eye dominance (p=1.0). Grants. This study did not require any funding.

  Publisher

Frequent coauthors

• Deborah M. Stephens

  University of North Carolina at Chapel Hill

  10 shared

• Anu Sharma

  University of Utah

  10 shared

• Anu Sharma

  3 shared

• Karma Elliott

  University of Utah

  2 shared

• Katie Kaput

  University of Utah

  2 shared

• Matthew Wahl

  University of Utah

  2 shared

• Arthur Joseph

  Palmetto General Hospital

  1 shared

• Angie Alegria

  1 shared

Labs

• UTAH DIABETES CENTERPI