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Neena Mirani

Neena Mirani

· Associate Professor

Rutgers University · Ophthalmology and Visual Science

Active 1988–2024

h-index21
Citations2.3k
Papers14816 last 5y
Funding
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About

Dr. Neena Mirani completed her MBBS in 1970 from Topiwala National Medical College and finished her Pathology residency in both Anatomic Pathology (AP) and Clinical Pathology (CP). She is a diplomate in Anatomic Pathology, Clinical Pathology, and Cytopathology. With over 20 years of experience as an attending and Director of Laboratory at a major teaching, university-affiliated hospital, she has broad administrative responsibilities and was a CAP inspector for several years. Her expertise includes Ophthalmic Pathology, Head and Neck Pathology, and Cytopathology, along with extensive experience in general surgical pathology. Since joining UMDNJ 18 years ago, she has provided pathology services and consultation to Ophthalmology and Head and Neck Surgery, and has been involved in teaching medical and dental students as well as residents in these specialties. Dr. Mirani has published more than 60 articles and numerous posters and abstracts, and she participates in research projects. She is a member of the hospital committee and holds licensure in New Jersey.

Research topics

  • Medicine
  • Surgery
  • Radiology
  • Pathology

Selected publications

  • Adenoid Cystic Carcinoma of the Lacrimal Glands: A Single Institute Experience

    International Journal of Surgical Pathology · 2024-06-05

    articleSenior author
  • Differentiation of intracranial Rosai‐Dorfman histiocytosis from meningioma using MR perfusion

    Clinical Case Reports · 2022 · 6 citations

    • Medicine
    • Radiology
    • Pathology

    Intracranial Rosai-Dorfman disease may be indistinguishable from meningioma. This distinction is essential, as they are treated very differently. We present two cases where perfusion imaging helped make this distinction, allowing one to be treated successfully without craniotomy. Perfusion imaging may be a powerful adjunct in cases where RDD mimics meningioma.

  • Large oral cavity cancer with anterior mandible invasion: Describing radiographic and pathologic discrepancy

    Oral Oncology Reports · 2022-03-01 · 1 citations

    articleOpen access

    /Hypothesis—Large oral cavity carcinoma can invade the mandible in the absence of radiographic findings. We hypothesize that the anterior mandible is at a unique elevated risk of subclinical invasion secondary to specific anatomic factors, described herein. —Adult patients managed from January 2012 to April 2020 ​at two large academic medical centers with large oral cavity carcinoma abutting anterior mandible were reviewed. A review of our institutional free flap databases was conducted selecting for bony reconstruction of anterior mandible defects. Cases were selected that did not have bone invasion seen on preoperative imaging but did have pathologic bone invasion on final pathology. —We present a Case series of four adult patients that were identified over the study duration. Subsites included three oral tongue and one floor of mouth. Three patients had squamous cell carcinoma and one patient had adenocarcinoma. Bony invasion was not appreciated on radiographic imaging, however final pathology demonstrated invasion in all patients. All patients had infiltrative pattern of mandibular invasion. —Mandible invasion, including presence of tumor in the medullary space, is possible even in the absence of radiographic bone invasion. The genial tubercle and lingual foramen may serve as an avenue of tumor spread into the anterior mandible from large oral cavity carcinoma. Surgical management of the mandible should be considered in select cases of large oral cavity carcinoma without radiographic evidence of mandible invasion.

  • Orbital impalement by ballyhoo fish beak

    Orbit · 2021-01-11

    article

    A 27-year-old woman snorkeling in Barbados surfaced and was struck in the left lower eyelid by an airborne fish, later identified as a ballyhoo (Figure 1A). Six days later, she presented with incre...

  • Spontaneous Suprachoroidal Hemorrhage as a Complication of Tissue Plasminogen Activator Use

    EC Ophthalmology · 2020-07-30

    article
  • Optic nerve and ophthalmic artery avulsion following gun shot wound

    Orbit · 2020-06-23

    article

    A 14 year-old male, intubated in the field following a self-inflicted cranial gunshot wound, had bilateral subdural hemorrhages requiring emergent neurosurgical decompressive hemicraniectomy. Conco...

  • Orbital cellulitis, sinusitis and intracranial abnormalities in two adolescents with COVID-19

    Orbit · 2020 · 106 citations

    • Medicine
    • Surgery

    We review two cases of adolescents with orbital cellulitis, sinusitis and SARS- CoV-2 infection presenting to emergency departments within a 24 hour period. SARS-CoV-2 samples obtained within 24 hours were positive, supporting prior infection despite relatively limited early symptoms of COVID-19. Unusual clinical and radiographic characteristics included hemorrhagic abscess with blood of varying age in the first, intracranial epidural abscess in the second, radiographic signal consistent with hemorrhagic or thrombotic phenomena, retro-maxillary antral fat changes, and meningeal enhancement or extension in both cases. Radiographic findings thereby mimic fungal infection, although final cultures and ancillary investigation for allergic and invasive fungal disease have remained negative. These cases highlight two unusual orbital presentations of cellulitis occurring in the context of SARS-CoV-2 co-infection.

  • Conjunctival Mucoepidermoid Carcinoma: a Case Reportand Review of the Literature

    EC Ophthalmology · 2020-12-31

    article
  • Idiopathic Terminal Ileal Ulceration Mimicking Crohn's in the Setting of Antiretroviral Therapy Initiation

    ACG Case Reports Journal · 2020-12-01

    articleOpen access

    Antiretroviral therapy (ART) has precipitously decreased the morbidity associated with human immunodeficiency virus but can unmask and exacerbate opportunistic infections and autoimmune diseases. Various diseases have been reported in association with ART initiation, but there is scant literature describing inflammatory colitis in the setting of ART initiation. We present a 39-year-old man with chronic untreated human immunodeficiency virus and central nervous system toxoplasmosis who developed persistent diarrhea after initiation of ART. A comprehensive infectious workup was negative. Computed tomography demonstrated terminal ileum enteritis, which was confirmed by colonoscopy. Biopsy of the terminal ileum revealed fibrinous exudate and granulation tissue.

  • Chronic, Symptomatic Orbital Inflammation Resulting From Retained Bone Wax

    Ophthalmic Plastic and Reconstructive Surgery · 2019-10-08 · 6 citations

    articleCorresponding

    A 58-year-old man presented with a 9-month history of a chronically draining surgical wound and low-grade periorbital inflammation following a right lateral orbitotomy. Imaging of the right orbit revealed a peculiar lesion in the right lateral orbit that was hypointense on both T1- and T2-weighted MRI with peripheral enhancement. Exploratory orbitotomy and biopsy established the diagnosis of a chronic foreign body inflammatory reaction to bone wax; symptoms resolved following evacuation of the retained foreign material.A 58-year-old man developed a chronic, symptomatic, inflammatory reaction to bone wax following a lateral orbitotomy; only once previously has symptomatic orbital inflammation following orbital surgery as a result of bone wax been reported.

Frequent coauthors

Education

  • Other

    Topiwala National Medical College

    1970
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