
Qing Li Wu
· Associate Research ProfessorVerifiedRutgers University · Medicinal Chemistry
Active 1997–2026
Research topics
- Chemistry
- Chromatography
- Pharmacology
- Materials science
- Food science
- Engineering
- Internal medicine
- Biochemical engineering
- Biology
- Nanotechnology
- Organic chemistry
- Endocrinology
- Medicine
Selected publications
Journal of Alloys and Compounds · 2026-04-22
articleSSRN Electronic Journal · 2026-01-01
preprintOpen accessMetallurgical and Materials Transactions A · 2025-03-17
articleSSRN Electronic Journal · 2025-01-01
preprintOpen accessGeophysical Research Letters · 2025-04-15 · 4 citations
articleOpen accessAbstract Antarctic warm extremes in winter have been one of major concerns because they are sometimes associated with anomalous snowfall and thus increase surface mass balance. Station observations and ERA5 showed that East Antarctic Ice Sheet (EAIS) experienced an unprecedented warm late‐winter (July‐August) in 2024 since the late 1950s. Record‐breaking positive Western Pacific Warm Pool (WP) and negative Pacific Decadal Oscillation in July‐August 2024 induced more frequent strong blocking highs over EAIS. Meanwhile, the stratospheric polar vortex weakened and elongated, and a record‐negative Southern Annular Mode was observed in August. They caused favorable circulation for atmospheric rivers (ARs) with warm moist air to frequently landfall on EAIS. Heat domes triggered by high‐pressure and net longwave radiation anomalies caused by intense moisture transport were largely responsible for the warm late‐winter. Our findings underscored the crucial role of tropic teleconnection in mechanism underlying warm extremes during Antarctic winter.
Journal of Food Science · 2025-04-01 · 1 citations
articleOpen accessSensory and phytochemical analyses were conducted on sweet basil (Ocimum basilicum L.) to investigate the impact of volatile and phenolic compounds on aroma, taste, and flavor by mouth. A trained panel evaluated seven accessions, including 'Aroma 2', 'Nufar', 'CB19', and four breeding lines developed by Rutgers for downy mildew resistance (DMR). The basils selected for this study displayed unique sensory profiles that were chemically characterized with 21 volatile and 15 phenolic compounds using GC/MS and LC/MS, respectively. Principal component analysis revealed a two-factor model. Factor 1 described cinnamon, floral, ginger, lemon, and musty aromas, clustering with eucalyptol and many minor aromatic compounds. 'Rutgers Thunderstruck-DMR' closely aligned with these attributes. Factor 2 described an axis with clove aroma/flavor and bitter taste on one end and anise and sweet aroma/taste on the opposite end. Anise aroma/flavor was closely associated with methyl chavicol and sweet aroma/flavor. Eugenol and several phenolic acids clustered near bitter taste. However, not all phenolic acids contributed to bitterness or astringency, suggesting diverse roles in sensory perception. 'Aroma 2', 'Rutgers Passion DMR', and 'Rutgers Obsession DMR' were aligned with the clove/spicy/bitter pole of Factor 2, whereas 'CB19' was oppositely aligned with the anise/sweet pole. 'Nufar' and 'Rutgers Devotion DMR' occupied the center of the plot and were characterized as moderate in their sensory/phytochemical profiles. In conclusion, this study reveals that new varieties can be distinguished by their sensory/phytochemical profiles and compared to commercial cultivars. Further, the inclusion of phenolic compounds led to more precise sensory/phytochemical descriptions of these varieties. PRACTICAL APPLICATION: This research provides valuable insights into the aroma, flavor, and underlying phytochemistry of fresh basil, which can help improve its taste and quality for culinary use. Sensory scientists and breeders can use the tools presented in this study as a means of selecting basil varieties to identify 'off types' and enhance aroma and flavor profiles.
SSRN Electronic Journal · 2025-01-01
preprintOpen accessThe Journal of Immunology · 2025-11-01
articleOpen accessAbstract Description SLE is a chronic autoimmune disease characterized by the generation of autoantibodies that promote tissue injury. Obesity is considered as a chronic inflammatory status and risk factor for autoimmune disease. Our previous data showed that lupus pathogenesis was exacerbated in obese SLE patients. Here we investigated the immune cell profile and clinicopathological features in obese SLE patients. Blood specimens were collected from 41 consented SLE patients with non-obese (BMI≤25, n = 10), overweight (BMI 25-30, n = 8), and obese (BMI≥30, n = 23). Immune cell profile was examined by flow cytometry. Clinical data were extracted from EPIC. Statistical significance and correlation were determined by Student’s t-test and Chi’s squared test. Obese and overweight SLE patients had a significantly more severe lupus (SLEDAI>6) than nonobese lupus patients (p < 0.01). Urine protein/creatinine ratio (p < 0.05), CRP (p < 0.005) and ESR level (p < 0.05) were significantly increased in obese SLE patients. Complement levels were correlated to patients’ BMI levels (P < 0.05). In addition, the increased frequencies of circulating Th2 (r = 0.8910) and Tfh helper cells (r = 0.5902) were observed in obese SLE patients, which were significantly correlated to SLEDAI level (p < 0.05). Our results showed that obese SLE patients had an altered Th2/Tfh helper cell profile and dysfunctional clinical features with worse outcomes. Further mechanism study may provide preventive and treatment strategies for obese SLE patients. Funding Sources LSUHS and Ochsner Collaborative Intramural Research Program (CIRP) Topic Categories Immune Mechanisms of Human Disease (HUM)
Journal of Chromatography B · 2024-06-04 · 1 citations
articleSenior authorCorrespondingFood Chemistry · 2024-08-05 · 10 citations
articleSenior authorCorresponding
Frequent coauthors
- 114 shared
James E. Simon
Rutgers Sexual and Reproductive Health and Rights
- 75 shared
William Sciarappa
Rutgers, The State University of New Jersey
- 71 shared
Peter Nitzsche
Rutgers, The State University of New Jersey
- 67 shared
Mingfu Wang
- 57 shared
Jim Simón
Rutgers, The State University of New Jersey
- 54 shared
Jeffrey P. Mitchell
University of California Division of Agriculture and Natural Resources
- 54 shared
Doug Monks
North Central State College
- 54 shared
Aref A. Abdul‐Baki
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