About
We use structural biology tools, primarily cryo-EM, to understand how proteins interact with membranes. We focus on how protein complexes assemble on membranes to bud and fuse vesicles during membrane trafficking.
Research topics
- Cell biology
- Chemistry
- Biology
- Computer Science
- Biophysics
- Materials science
- Genetics
- Computational biology
Selected publications
Membrane Technology and Applications
2023 · 512 citations
1st authorCorresponding- Computer Science
- Materials science
- Computer Science
Membrane Technology and Applications Internationally acknowledged text on separation membrane technology, presenting current theory and practice, plus manufacturing and applications The 4th Edition of Membrane Technology and Applications presents an authoritative, up-to-date overview of separation membranes, their theoretical underpinnings, manufacture, and use, beginning with a series of general chapters on membrane preparation, transport theory, and concentration polarization, then surveying the major areas of membrane application in separate chapters. Written in a readily accessible style, each chapter offers a thorough treatment of its subject, from historical and theoretical backgrounds through to current and potential applications. Topics include reverse osmosis, ultrafiltration, microfiltration, gas separation, pervaporation, electrodialysis, coupled and facilitated transport, and medical applications of membranes. This new edition has been comprehensively updated, with substantial new material, figures, and references throughout to reflect the latest developments in the field. Major changes include: A new chapter on transport mechanisms in finely microporous membranes, with focus on gas transport A new chapter on membrane contactors A substantially expanded section on hyperfiltration applications, including pharmaceutical applications, in the reverse osmosis chapter Expanded treatment of membrane bioreactors, plus a new section on biotechnology applications, in the ultrafiltration chapter A new section in the gas separation chapter devoted to carbon dioxide capture from industrial process emissions, including power plant emissions Research areas that the author would work on if he were, once again, a 21-year-old graduate student. Written by a leading expert with 50 years of experience, Membrane Technology and Applications provides balanced coverage of all aspects of the field, and is essential reading for all membrane enthusiasts, from neophyte graduate student to academic researcher to seasoned industry professional.
LIS1 promotes the formation of activated cytoplasmic dynein-1 complexes
Nature Cell Biology · 2020 · 139 citations
- Cell biology
- Chemistry
- Biology
Structural insights into assembly and function of the RSC chromatin remodeling complex
Nature Structural & Molecular Biology · 2020 · 38 citations
1st authorCorresponding- Cell biology
- Computational biology
- Chemistry
Frequent coauthors
- 12 shared
Andres E. Leschziner
University of California, San Diego
- 9 shared
Kevin S. Cannon
University of North Carolina at Chapel Hill
- 8 shared
Tanita Tedamrongwanish
Communities In Schools of Orange County
- 8 shared
Reta D. Sarsam
University of North Carolina at Chapel Hill
- 8 shared
Kevin Zhang
Communities In Schools of Orange County
- 8 shared
Zaw Min Htet
Berkeley College
- 7 shared
Tsutomu Arakawa
Digital Research Alliance of Canada
- 7 shared
Frederick M. Hughson
Princeton University
Labs
Education
- 2015
PhD, Molecular Biology
Princeton University
- 2008
B.S., Biology
Univeristy of North Carolina, Chapel Hill
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