Takeyoshi Ota
· Research Assistant Professor of SurgeryUniversity of Chicago · Surgery
Active 1992–2026
Research topics
- Cardiology
- Medicine
- Internal medicine
- Surgery
- Anesthesia
Selected publications
Journal of the Society for Cardiovascular Angiography & Interventions · 2026-04-01
articleOpen accessJournal of the American College of Cardiology · 2026-03-27
articleThe Journal of Heart and Lung Transplantation · 2025-04-01
articleOpen accessJournal of Cardiac Failure · 2025-02-13 · 8 citations
articleTwo-staged aortic repair for acute type A aortic dissection in patients refusing blood transfusion
Vascular · 2025-02-17 · 1 citations
articleBackground It is still challenging to perform high-risk cases, such as acute type A dissection, which frequently require blood transfusions. We created perioperative bloodless protocol, but it includes an optimization to increase the preoperative hemoglobin level enough to tolerate cardiopulmonary bypass. However, it would be impossible to optimize such patients using the strategy in the setting of emergent surgery. We sought to create a surgical strategy in an effort to reduce blood loss for acute type A dissection patients refusing blood transfusion. Methods We reviewed the records of two patients in our aortic surgery database who presented with acute aortic dissection and refused blood transfusion. These patients underwent two-staged aortic repair with ascending aortic replacement with debranching to the innominate and left common carotid arteries, followed by thoracic endovascular aortic repair (TEVAR). Results : The two-staged procedure was successfully completed in two patients without any significant complication. The postoperative course was uneventful for both patients. Conclusion Two-staged aortic repair in patients refusing blood transfusion can avoid circulatory arrest requiring deep hypothermia so as to reduce the risk of coagulopathy and blood loss.
Mechanisms of Cardiac Implantable Electronic Device Interference With the Tricuspid Valve Apparatus
The American Journal of Cardiology · 2025-04-23
articleTrauma Surgery & Acute Care Open · 2024-12-01
articleOpen accessCase presentation A patient in their 50s presented as a level-2 trauma activation after a motor vehicle collision.
Journal of the American College of Cardiology · 2024-04-01
articleEarly and Late Outcomes of Ambulatory Counter Pulsation Devices as a Bridge to Heart Transplantation
Cardiology · 2024-11-29
articleSenior authorINTRODUCTION: The intravascular ventricular assist device is a newly developed ambulatory and portable counter pulsation heart assist system. The purpose of this study was to compare the early and late outcomes of counter pulsation devices between intravascular ventricular assist system (iVAS) and axillary intra-aortic balloon pump (IABP) as a bridge to heart transplantation. METHODS: This is a single-center, retrospective study. Between April 2016 and March 2020, 24 patients underwent iVAS implantation (Group A), and 73 patients underwent axillary IABP (Group B) as a bridge to heart transplantation. We reviewed and compared perioperative data, as well as late survival outcomes. RESULTS: There were no significant differences in baseline characteristics. All patients in Group A and 97.3% of patients in Group B were able to ambulate and participate in physical therapy (p = 0.28). There were no in-hospital deaths in the two groups. The median duration of device support in Group A was significantly longer than in Group B (A: 37.0 days vs. B: 15.0 days, p < 0.01). After the US Food and Drug Administration approved the discharge of patients with an iVAS, 4 patients (4/14, 28.6%) were discharged home with the device. The success rate of bridge to transplantation was not significantly different between the groups (A: 21/24, 87.5% vs. B: 68/73, 93.2%, p = 0.40). Late survival after heart transplantation also did not differ between the groups (A: 85.7% at 3-year vs. B: 94.0% at 3-year, log rank = 0.22). CONCLUSION: Both iVAS and axillary IABP showed comparable success rates of bridge to transplantation and late survival after transplantation. The mobile design of iVAS facilitated excellent ambulatory capability and enabled patients to be discharged home.
Interdisciplinary CardioVascular and Thoracic Surgery · 2023-07-01
articleOpen accessSenior authorOBJECTIVES: It remains unknown if the left atrial appendage closure (LAAC) at the time of left ventricular assist device (LVAD) surgery can reduce ischaemic cerebrovascular accidents. METHODS: Consecutive 310 patients who underwent LVAD surgery with HeartMate II or 3 between January 2012 and November 2021 were included in this study. The cohort was divided into 2 groups: patients with LAAC (group A) and without LAAC (group B). We compared the clinical outcomes including the incidence of cerebrovascular accident between 2 groups. RESULTS: Ninety-eight patients were included in group A, and 212 patients in group B. There were no significant differences between 2 groups in age, preoperative CHADS2 score and history of atrial fibrillation. In-hospital mortality did not differ significantly between the 2 groups (group A: 7.1%, group B: 12.3%, P = 0.16). Thirty-seven patients (11.9%) experienced ischaemic cerebrovascular accident (5 patients in group A and 32 patients in group B). The cumulative incidence from ischaemic cerebrovascular accidents in group A (5.3% at 12 months and 5.3% at 36 months) was significantly lower than that in group B (8.2% at 12 months and 16.8% at 36 months; P = 0.017). In a multivariable competing risk analysis, LAAC was associated with reducing ischaemic cerebrovascular accidents (hazard ratio 0.38, 95% confidence interval 0.15-0.97, P = 0.043). CONCLUSIONS: Concomitant LAAC in LVAD surgery can reduce ischaemic cerebrovascular accidents without increasing perioperative mortality and complications.
Frequent coauthors
- 202 shared
Valluvan Jeevanandam
University of Chicago Medical Center
- 179 shared
Nir Uriel
Columbia University Irving Medical Center
- 113 shared
T. Song
- 109 shared
G. Sayer
- 92 shared
Gene Kim
- 77 shared
J. Raikhelkar
Columbia University Irving Medical Center
- 74 shared
Sara Kalantari
Shaheed Rajaei Cardiovascular Medical and Research Center
- 73 shared
B. Smith
University of Illinois Chicago
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