About

Edward Ming-Iuan Gong is an Associate Professor in the Department of Urology at Northwestern University Feinberg School of Medicine, specializing in Pediatric Urology. He is affiliated with the Center for Reproductive Science, Northwestern University Clinical and Translational Sciences Institute (NUCATS), and the Stanley Manne Children's Research Institute. His professional focus includes pediatric urological conditions, with an emphasis on reproductive science and related research areas. The page does not provide additional details about his research contributions, background, or specific achievements.

Research topics

• Surgery
• Medicine
• Internal medicine
• General surgery
• Operations management
• Medical physics

Selected publications

• A case report of paratesticular rhabdomyosarcoma management: Orchiectomy, pre-radiation testicular transposition, and post-radiation orchiopexy

  Urology Case Reports · 2025-06-06

  articleOpen access

  Paratesticular rhabdomyosarcoma is a rare malignancy with favorable prognosis when treated with radical inguinal orchiectomy ± chemotherapy and radiation for patients with advanced disease. When scrotal radiation is indicated, testicular preservation is a pivotal consideration. A widely accepted recommendation is temporary transposition of the remaining testicle to a thigh pouch prior to initiation of radiation. Here, we describe the clinical course of a young patient with paratesticular rhabdomyosarcoma and our unique operative approach using a Bianchi incision during thigh pouch creation to allow for groin preservation followed by a staged inguinal approach for post-radiation orchiopexy.

  PublisherDOI

• IP20-38 CYSTOSTOMY BUTTON: A REPURPOSED GASTROSTOMY TUBE OFFERS A SAFE, CONTINENT ALTERNATIVE FOR SELECTED CHILDREN WITH POOR BLADDER EMPTYING

  The Journal of Urology · 2025-04-08

  article
  PublisherDOI

• Exploring the Landscape of Aptamers: From Cross-Reactive to Selective to Specific, High-Affinity Receptors for Cocaine

  JACS Au · 2024-02-13 · 28 citations

  articleOpen access

  We reported over 20 years ago MNS-4.1, the first DNA aptamer with a micromolar affinity for cocaine. MNS-4.1 is based on a structural motif that is very common in any random pool of oligonucleotides, and it is actually a nonspecific hydrophobic receptor with wide cross-reactivity with alkaloids and steroids. Despite such weaknesses preventing broad applications, this aptamer became widely used in proof-of-concept demonstrations of new formats of biosensors. We now report a series of progressively improved DNA aptamers recognizing cocaine, with the final optimized receptors having low nanomolar affinity and over a thousand-fold selectivity over the initial cross-reactants. In the process of optimization, we tested different methods to eliminate cross-reactivities and improve affinity, eventually achieving properties that are comparable to those of the reported monoclonal antibody candidates for the therapy of overdose. Multiple aptamers that we now report share structural motifs with the previously reported receptor for serotonin. Further mutagenesis studies revealed a palindromic, highly adaptable, broadly cross-reactive hydrophobic motif that could be rebuilt through mutagenesis, expansion of linker regions, and selections into receptors with exceptional affinities and varying specificities.

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• Robotic-assisted Pediatric Thoracic and Abdominal Tumor Resection: An Initial Multi-center Review

  Journal of Pediatric Surgery · 2024-02-26 · 8 citations

  article
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• Robot-assisted Laparoscopic Pyeloplasty: Experience of a Single Pediatric Institution, Including Long-term and Safety Outcomes

  Urology · 2023-03-31 · 7 citations

  articleOpen access
  PublisherOA PDFDOI

• Growth in Newborn Circumcisions Performed by Pediatric Urologists and Advanced Practice Providers Between 2010 and 2021 in the United States

  Urology · 2023-11-17 · 5 citations

  article
  PublisherDOI

• Clinical considerations in adults with history of posterior urethral valves

  Journal of Pediatric Urology · 2023-09-15 · 6 citations

  reviewCorresponding
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• Response to commentary re retrograde incision from orifice (RIO) technique for endoscopic incision of ureterocele: 15 years of outcomes

  Journal of Pediatric Urology · 2023-06-24 · 1 citations

  letterSenior author
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• PD37-06 GROWTH IN NEWBORN CIRCUMCISIONS PERFORMED BY PEDIATRIC UROLOGISTS AND ADVANCED PRACTICE PROVIDERS FROM 2010-2020 IN THE UNITED STATES

  The Journal of Urology · 2023-03-23

  article

  You have accessJournal of UrologyCME1 Apr 2023PD37-06 GROWTH IN NEWBORN CIRCUMCISIONS PERFORMED BY PEDIATRIC UROLOGISTS AND ADVANCED PRACTICE PROVIDERS FROM 2010-2020 IN THE UNITED STATES Emilie Johnson, Hyman, Camille Hardy Maizels, Catherine Seager, Derek Matoka, Dennis Liu, Edward Gong, Jane Holl, and Modi Parth Emilie JohnsonEmilie Johnson More articles by this author , Hyman Hyman More articles by this author , Camille Hardy MaizelsCamille Hardy Maizels More articles by this author , Catherine SeagerCatherine Seager More articles by this author , Derek MatokaDerek Matoka More articles by this author , Dennis LiuDennis Liu More articles by this author , Edward GongEdward Gong More articles by this author , Jane HollJane Holl More articles by this author , and Modi ParthModi Parth More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003335.06AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Roughly 50% of boys born in the United States (US) undergo newborn circumcision (NC), most often by obstetricians or pediatricians before hospital discharge. Anecdotally, pediatric urologists are facing increasing NC demand due to factors including declining clinician interest and staffing shortages. A few institutions have also recently reported experiences with advanced practice providers (APPs) performing NC. To illuminate recent practice patterns more fully, this study analyzed the proportion of NCs performed by different specialists over time. METHODS: The IBM® MarketScan® Commercial Database was queried for NC private health insurance claims (Common Procedural Terminology 54150) between 2010 and 2020. Setting (inpatient/outpatient), US region, clinician specialty, and patient age (days) were determined for the full study time-period, and by study year. Simple linear regression assessed growth in proportion of NCs performed by pediatric urologists and APPs (nurse practitioner/physician assistant/midwife) over time. RESULTS: In total, 952,772 boys underwent NC (Table 1). Most NCs were inpatient (59%) by obstetricians (46%) or pediatricians (33%); APPs performed 0.8%, and pediatric urologists performed 0.6%. The proportion of NCs performed by pediatric urologists increased from 0.3% in 2010 to 1.7% in 2020, and for APPs increased from 0.5% to 2.3%, p<0.0001 for both (Figure 1). Growth for both APPs and pediatric urologists predominantly occurred from 2016 to 2020. In 2020, pediatric urologists and APPs performed the highest percentage of NCs in the South (2.9% & 2.5% respectively), followed by the Northeast (2.5% & 1.4% respectively). CONCLUSIONS: The proportion of NCs performed by pediatric urologists and APPs increased significantly between 2010 and 2020, though both specialties still perform a minority of NCs. These data provide important baseline information for NC workforce planning, including evaluating collaborative care models where pediatric urologists train APPs to perform NCs. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e989 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Emilie Johnson More articles by this author Hyman More articles by this author Camille Hardy Maizels More articles by this author Catherine Seager More articles by this author Derek Matoka More articles by this author Dennis Liu More articles by this author Edward Gong More articles by this author Jane Holl More articles by this author Modi Parth More articles by this author Expand All Advertisement PDF downloadLoading ...

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• Randomized trial of prophylactic antibiotics vs. placebo after midshaft-to-distal hypospadias repair: the PROPHY Study

  Journal of Pediatric Urology · 2022-01-24 · 14 citations

  article
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Frequent coauthors

• Bruce W. Lindgren

  78 shared

• Earl Y. Cheng

  Northwestern University

  57 shared

• Emilie K. Johnson

  Lurie Children's Hospital

  51 shared

• Dennis B. Liu

  Lurie Children's Hospital

  43 shared

• Diana K. Bowen

  Northwestern University

  43 shared

• Elizabeth B. Yerkes

  33 shared

• Ilina Rosoklija

  Lurie Children's Hospital

  30 shared

• Arieh L. Shalhav

  30 shared